干细胞治疗白癜风的基础及临床研究进展

doi:10.35541/cjd.20240127

中华皮肤科杂志 ›› 2024, e20240127.doi: 10.35541/cjd.20240127

干细胞治疗白癜风的基础及临床研究进展

张钰得王红娟康晓静

新疆维吾尔自治区人民医院皮肤性病科新疆皮肤性病临床医学研究中心新疆皮肤病研究重点实验室，乌鲁木齐 830001

收稿日期:2024-03-11 修回日期:2024-08-05 发布日期:2024-11-26
通讯作者: 康晓静 E-mail:drkangxj666@163.com
基金资助:
国家自然科学基金（82173406）；新疆维吾尔自治区人民医院干细胞生物治疗基础和临床研究专项（GXBZX-2023001）

Stem cell therapy for vitiligo: advances in basic and clinical research

Zhang Yude, Wang Hongjuan, Kang Xiaojing

Department of Dermatology and Venereology, People' s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Clinical Research Center for Dermatology and Venereology, Xinjiang Key Laboratory of Dermatology Research, Urumqi 830001, China

Received:2024-03-11 Revised:2024-08-05 Published:2024-11-26
Contact: Kang Xiaojing E-mail:drkangxj666@163.com
Supported by:
National Natural Science Foundation of China （82173406）; Basic and Clinical Research Special Project of Stem Cell Biotherapy at People′s Hospital of Xinjiang Uygur Autonomous Region （GXBZX-2023001）

摘要/Abstract

摘要： 【摘要】干细胞是一类具有自我更新和分化能力的细胞，可通过分化为黑素细胞填补受损皮肤中的色素缺失区域，对抗自身免疫和氧化应激损伤造成的黑素细胞凋亡以及联合传统疗法提高复色率。研究表明，干细胞疗法应用于白癜风复色疗效显著。本文综述干细胞应用于白癜风治疗的基础和临床研究最新进展。

关键词: 白癜风, 干细胞, 黑素细胞, 自身免疫, 氧化性应激

Abstract: 【Abstract】 Stem cells are a kind of cells with the ability of self-renewal and differentiation, which can differentiate into melanocytes to fill the areas of pigment loss in damaged skin, fight against the apoptosis of melanocytes caused by autoimmunity and oxidative stress damage, and improve repigmentation rates in combination with traditional therapies. Studies have shown significant efficacy of stem cell therapy in the repigmentation of vitiligo. This review summarizes the latest advances in the basic and clinical research on the application of stem cells in the treatment of vitiligo.

Key words: Vitiligo, Stem cells, Melanocytes, Autoimmunity, Oxidative stress

中图分类号:

张钰得王红娟康晓静. 干细胞治疗白癜风的基础及临床研究进展[J]. 中华皮肤科杂志, 2024,e20240127. doi:10.35541/cjd.20240127

Zhang Yude, Wang Hongjuan, Kang Xiaojing. Stem cell therapy for vitiligo: advances in basic and clinical research[J]. Chinese Journal of Dermatology,2024,e20240127. doi:10.35541/cjd.20240127

参考文献 31

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干细胞治疗白癜风的基础及临床研究进展

Stem cell therapy for vitiligo: advances in basic and clinical research

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