毛囊及毛囊细胞移植在白癜风治疗中的应用进展

doi:10.35541/cjd.20230274

中华皮肤科杂志 ›› 2024, e0230274.doi: 10.35541/cjd.20230274

毛囊及毛囊细胞移植在白癜风治疗中的应用进展

戴叶芹^1，2 宋秀祖²

¹浙江大学医学院，杭州 310000；²杭州市第三人民医院皮肤科，杭州 310009

收稿日期:2023-05-15 修回日期:2023-07-04 发布日期:2024-01-29
通讯作者: 宋秀祖 E-mail:songxiuzu@sina.com.cn
基金资助:
浙江省基础公益研究项目（LY23H110001）

Application of hair follicle transplantation and follicular cell suspension transplantation in the treatment of vitiligo

Dai Yeqin^1,2, Song Xiuzu²

¹Zhejiang University School of Medicine, Hangzhou 310000, China; ²Department of Dermatology, Hangzhou Third People′s Hospital, Hangzhou 310009, China

Received:2023-05-15 Revised:2023-07-04 Published:2024-01-29
Contact: Song Xiuzu E-mail:songxiuzu@sina.com.cn
Supported by:
Basic Public Welfare Research Project of Zhejiang（LY23H110001）

摘要/Abstract

摘要： 【摘要】白癜风是一种常见的后天色素脱失性皮肤病，因表皮黑素细胞和毛囊黑素细胞功能丧失或数量减少引起，可影响皮肤和毛发。白癜风治疗的主要原则是控制病情进展使之稳定后，促使皮损区色素恢复，达到形态和功能上的修复。皮肤和毛囊黑素细胞作为白斑复色的主要来源，常被用于将整个组织或组织来源的细胞悬液移植到白癜风皮损区域。本文综述毛囊组织及毛囊细胞移植在白癜风外科治疗中的应用进展。

关键词: 白癜风, 毛囊, 移植, 自体, 黑素细胞, 治疗

Abstract: 【Abstract】 Vitiligo is a common acquired depigmentation skin disease involving the skin and hair, which is caused by the loss of function of or reduction in the number of epidermal melanocytes and hair follicle melanocytes. The main principle of treatment is to control the disease progression, promote the repigmentation in lesional areas, and achieve morphological and functional repair. Skin and hair follicle melanocytes are the main source of vitiligo repigmentation, and thus transplantation of the whole tissues or tissue-derived cell suspensions to the vitiligo lesions is often used for the treatment of vitiligo. This review summarizes the progress in the application of hair follicle transplantation and follicular cell suspension transplantation in the surgical treatment of vitiligo.

Key words: Vitiligo, Hair follicle, Transplantation, autologous, Melanocytes, Therapy

戴叶芹宋秀祖. 毛囊及毛囊细胞移植在白癜风治疗中的应用进展[J]. 中华皮肤科杂志, 2024,e0230274. doi:10.35541/cjd.20230274

Dai Yeqin, Song Xiuzu. Application of hair follicle transplantation and follicular cell suspension transplantation in the treatment of vitiligo[J]. Chinese Journal of Dermatology,2024,e0230274. doi:10.35541/cjd.20230274

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毛囊及毛囊细胞移植在白癜风治疗中的应用进展

Application of hair follicle transplantation and follicular cell suspension transplantation in the treatment of vitiligo

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