中华皮肤科杂志 ›› 2021, Vol. 54 ›› Issue (11): 1019-1022.doi: 10.35541/cjd.20200152

• 综述 • 上一篇    下一篇

间充质干细胞在银屑病中的应用

王晓宇    张春雷    王文慧   

  1. 北京大学第三医院皮肤科  100191
  • 收稿日期:2020-02-22 修回日期:2021-01-06 发布日期:2021-11-01
  • 通讯作者: 王文慧 E-mail:wwh0608@126.com
  • 基金资助:
    国家自然科学基金(81972560);北京自然科学基金(7202231);米尔斯坦亚美医学基金(2019MMAAP)

Application of mesenchymal stem cells in psoriasis

Wang Xiaoyu, Zhang Chunlei, Wang Wenhui   

  1. Department of Dermatology, Peking University Third Hospital, Beijing 100191, China
  • Received:2020-02-22 Revised:2021-01-06 Published:2021-11-01
  • Contact: Wang Wenhui E-mail:wwh0608@126.com
  • Supported by:
    National Natural Science Foundation of China (81972560); Beijing Municipal Natural Science Foundation(7202231); Milstein Medical Asian American Partnership Foundation Research Project Award (2019MMAAP)

摘要: 【摘要】 间充质干细胞是干细胞家族的重要成员,具有自我更新、多向分化潜能和免疫调节作用及低免疫原性等特点。有文献报告间充质干细胞用于治疗银屑病获得不同程度的疗效,且有较长的疾病缓解期。本文综述间充质干细胞在银屑病中的应用及相关研究进展。

关键词: 银屑病, 间充质干细胞, 治疗, 复发

Abstract: 【Abstract】 Mesenchymal stem cells are an important member of the stem cell family, characterized by self-renewal ability, multipotent differentiation potential, immunomodulatory effects, low immunogenicity, etc. Studies have demonstrated varying degrees of clinical efficacy of mesenchymal stem cells in the treatment of psoriasis, with long remission periods. This review summarizes the application of mesenchymal stem cells in psoriasis and related research progress.

Key words: Psoriasis, Mesenchymal stem cells, Therapy, Recurrence