儿童期痤疮

doi:10.35541/cjd.20190903

中华皮肤科杂志 ›› 2021, Vol. 54 ›› Issue (3): 273-275.doi: 10.35541/cjd.20190903

• 综述 • 上一篇

儿童期痤疮

耿雯瑾,刘彤云

昆明医科大学第一附属医院皮肤科 650031

收稿日期:2019-09-16 修回日期:2020-05-14 发布日期:2021-03-02
通讯作者: 刘彤云 E-mail:tongyun91@126.com

Childhood acne

Geng Wenjin, Liu Tongyun

Department of Dermatology, The First Affiliated Hospital of Kunming Medical University, Kunming 650031, China

Received:2019-09-16 Revised:2020-05-14 Published:2021-03-02
Contact: Liu Tongyun E-mail:tongyun91@126.com

摘要/Abstract

摘要： 【摘要】根据发病年龄可将儿童期痤疮分为新生儿痤疮、婴儿痤疮、学龄前儿童痤疮、青春期前痤疮。新生儿痤疮和婴儿痤疮可作为青春期严重痤疮的预测因素，学龄前儿童痤疮可能与潜在内分泌疾病有关，青春期前痤

关键词: 寻常痤疮, 儿童, 雄激素类, 维甲酸

Abstract: 【Abstract】 According to the age of onset, childhood acne can be divided into neonatal acne, infantile acne, preschool acne, and prepubertal acne. Neonatal acne and infantile acne can serve as predictive factors for severe adolescent acne, preschool acne may be related to underlying endocrine diseases, and prepubertal acne is a sign of pubertal maturation. The treatment of childhood acne is similar to that of adolescent acne, and adverse effects of drugs and their impact on the growth and development of children should be considered.

Key words: Acne vulgaris, Child, Androgens, Tretinoin

耿雯瑾刘彤云. 儿童期痤疮[J]. 中华皮肤科杂志, 2021,54(3):273-275. doi:10.35541/cjd.20190903

Geng Wenjin, Liu Tongyun. Childhood acne[J]. Chinese Journal of Dermatology, 2021, 54(3): 273-275.doi:10.35541/cjd.20190903

参考文献 31

［1］	中国痤疮治疗指南专家组. 中国痤疮治疗指南（2019修订版）［J］. 临床皮肤科杂志, 2019,48（9）:583⁃588. doi: 10.16761/j.cnki.1000⁃4963.2019.09.020.
［2］	Eyüboglu M, Kalay I, Eyüboglu D. Evaluation of adolescents diagnosed with acne vulgaris for quality of life and psychosocial challenges［J］. Indian J Dermatol, 2018,63（2）:131⁃135. doi: 10. 4103/ijd.IJD_671_16.
［3］	Park MY, Kim KH, Kang H, et al. Analysis of Korean acne patients according to age groups based on two multicenter studies［J］. J Dermatol, 2017,44（2）:186⁃188. doi: 10.1111/1346⁃8138. 13642.
［4］	Özçelik S, Kulaç İ, Yazıcı M, et al. Distribution of childhood skin diseases according to age and gender, a single institution experience［J］. Turk Pediatri Ars, 2018,53（2）:105⁃112. doi: 10. 5152/TurkPediatriArs.2018.6431.
［5］	Maroñas⁃Jiménez L, Krakowski AC. Pediatric acne: clinical patterns and pearls［J］. Dermatol Clin, 2016,34（2）:195⁃202. doi: 10.1016/j.det.2015.11.006.
［6］	Eichenfield LF, Krakowski AC, Piggott C, et al. Evidence⁃based recommendations for the diagnosis and treatment of pediatric acne［J］. Pediatrics, 2013,131（Suppl 3）:S163⁃S186. doi: 10.1542/ peds.2013⁃0490B.
［7］	Ashton R, Weinstein M. Acne vulgaris in the pediatric patient［J］. Pediatr Rev, 2019,40（11）:577⁃589. doi: 10.1542/pir.2018⁃0137.
［8］	葛宏松, 周洁, 曹婷婷, 等. 56例新生儿痤疮临床分析［J］. 中国麻风皮肤病杂志, 2019,35（7）:404⁃405,418.
［9］	Šijak D, Horvat I, Sonicki Z, et al. Correlation between family history and the age of onset of childhood acne in relation to sex and type of acne［J］. Acta Dermatovenerol Croat, 2019,27（2）:86⁃89.
［10］	Choi CW, Kim Y, Kim JE, et al. Enhancement of lipid content and inflammatory cytokine secretion in SZ95 sebocytes by palmitic acid suggests a potential link between free fatty acids and acne aggravation［J］. Exp Dermatol, 2019,28（2）:207⁃210. doi: 10.1111/exd.13855.
［11］	Wang H, Wang J, Zhou M, et al. Prediction of neonatal acne based on maternal lipidomic profiling［J］. J Cosmet Dermatol, 2020,00:1⁃8. doi: 10.1111/jocd.13320.
［12］	Friedlander SF, Baldwin HE, Mancini AJ, et al. The acne continuum: an age⁃based approach to therapy［J］. Semin Cutan Med Surg, 2011,30（3 Suppl）:S6⁃S11. doi: 10.1016/j.sder.2011.07. 002.
［13］	Mwanthi M, Zaenglein AL. Update in the management of acne in adolescence［J］. Curr Opin Pediatr, 2018,30（4）:492⁃498. doi: 10.1097/MOP.0000000000000649.
［14］	Valente Duarte De Sousa IC. New and emerging drugs for the treatment of acne vulgaris in adolescents［J］. Expert Opin Pharmacother, 2019,20（8）:1009⁃1024. doi: 10.1080/14656566. 2019.1584182.
［15］	Zouboulis CC, Dessinioti C, Tsatsou F, et al. Anti⁃acne drugs in phase 1 and 2 clinical trials［J］. Expert Opin Investig Drugs, 2017,26（7）:813⁃823. doi: 10.1080/13543784.2017.1337745.
［16］	Chew EW, Bingham A, Burrows D. Incidence of acne vulgaris in patients with infantile acne［J］. Clin Exp Dermatol, 1990,15（5）:376⁃377. doi: 10.1111/j.1365⁃2230.1990.tb02119.x.
［17］	Zhou M, Wang H, Yang M, et al. Lipidomic analysis of facial skin surface lipid reveals the altered lipid profile in infancy acne［J］. Br J Dermatol, 2020,182（3）:817⁃818. doi: 10.1111/bjd.18474 .
［18］	Antoniou C, Dessinioti C, Stratigos AJ, et al. Clinical and therapeutic approach to childhood acne: an update［J］. Pediatr Dermatol, 2009,26（4）:373⁃380. doi: 10.1111/j.1525⁃1470.2009. 00932.x.
［19］	Admani S, Barrio VR. Evaluation and treatment of acne from infancy to preadolescence［J］. Dermatol Ther, 2013,26（6）:462⁃466. doi: 10.1111/dth.12108.
［20］	Miller IM, Echeverría B, Torrelo A, et al. Infantile acne treated with oral isotretinoin［J］. Pediatr Dermatol, 2013,30（5）:513⁃518. doi: 10.1111/pde.12069.
［21］	Dursun R, Daye M, Durmaz K. Acne and rosacea: what′s new for treatment?［J］. Dermatol Ther, 2019,32（5）:e13020. doi: 10.1111/ dth.13020.
［22］	Gurnee EA, Kamath S, Kruse L. Complementary and alternative therapy for pediatric acne: a review of botanical extracts, dietary interventions, and oral supplements［J］. Pediatr Dermatol, 2019,36（5）:596⁃601. doi: 10.1111/pde.13904.
［23］	王鸿, 邓永琼, 熊霞. 痤疮再认识［J］. 临床皮肤科杂志, 2019,48（12）:774⁃777. doi: 10.16761/j.cnki.1000⁃4963.2019.12.023.
［24］	Nguyen HL, Tollefson MM. Endocrine disorders and hormonal therapy for adolescent acne［J］. Curr Opin Pediatr, 2017,29（4）:455⁃465. doi: 10.1097/MOP.0000000000000515.
［25］	Bernal LE, Zarco AP, Campos P, et al. Rosácea infantil［J］. Bol Med Hosp Infant Mex, 2019,76（2）:95⁃99. doi: 10.24875/BMHIM. 18000032.
［26］	Amoroso S, Spagnut G, Robazza M, et al. From skin to bone: a boy with an unusual cause of acne［J］. Arch Dis Child, 2020,105（6）:600. doi: 10.1136/archdischild⁃2018⁃316620.
［27］	Martinez⁃Rios C, Jariwala MP, Highmore K, et al. Imaging findings of sterile pyogenic arthritis, pyoderma gangrenosum and acne （PAPA） syndrome: differential diagnosis and review of the literature［J］. Pediatr Radiol, 2019,49（1）:23⁃36. doi: 10.1007/s00247⁃018⁃4246⁃1.
［28］	Kazandjieva J, Tsankov N. Drug⁃induced acne［J］. Clin Dermatol, 2017,35（2）:156⁃162. doi: 10.1016/j.clindermatol.2016.10.007.
［29］	Que S, Whitaker⁃Worth DL, Chang MW. Acne: kids are not just little people［J］. Clin Dermatol, 2016,34（6）:710⁃716. doi: 10. 1016/j.clindermatol.2016.07.005.
［30］	Ahluwalia J, Borok J, Haddock ES, et al. The microbiome in preadolescent acne: assessment and prospective analysis of the influence of benzoyl peroxide［J］. Pediatr Dermatol, 2019,36（2）:200⁃206. doi: 10.1111/pde.13741.
［31］	Eichenfield LF, Sugarman JL, Guenin E, et al. Novel tretinoin 0.05% lotion for the once⁃daily treatment of moderate⁃to⁃severe acne vulgaris in a preadolescent population［J］. Pediatr Dermatol, 2019,36（2）:193⁃199. doi: 10.1111/pde.13744.

[1]	刘燕邱林傅跃先田晓菲袁心刚肖军李天武毛小波梅爱莲郭永强周荣. 儿童甲母痣35例外科治疗效果分析[J]. 中华皮肤科杂志, 2022, 0(4): 20201040-e20201040.
[2]	韩晓锋孙娟邱磊尉莉马琳. 儿童穿通型毛母质瘤29例临床病理特点分析[J]. 中华皮肤科杂志, 2022, 55(3): 196-199.
[3]	吴淑辉朱明芳张曦杨逸璇张娟娟. 牛奶对金黄地鼠皮脂腺斑及IGF-1/SREBP-1/ACC-1信号通路的影响[J]. 中华皮肤科杂志, 2022, 55(3): 238-242.
[4]	王召阳陈安薇向欣罗晓燕徐子刚王华马琳. 基于两家儿童医院信息系统的儿童银屑病现状调查[J]. 中华皮肤科杂志, 2022, 55(3): 246-250.
[5]	何瑞, 张斌, 李丽, 尉莉, 张楠, 于彤, 阴捷, 徐子刚, 马琳. 外用西罗莫司治疗儿童浅表脉管畸形19例的临床疗效及安全性分析[J]. 中华皮肤科杂志, 2022, 55(2): 129-134.
[6]	曹蒙洪安澜王焱方方. 儿童黑素瘤临床研究进展[J]. 中华皮肤科杂志, 2022, 0(1): 20210158-e20210158.
[7]	孔雪史冬梅刘维达. 抗真菌药在特殊人群的应用[J]. 中华皮肤科杂志, 2022, 55(1): 80-83.
[8]	中华医学会医学美学与美容学分会激光美容学组中华医学会皮肤性病学分会美容激光学组中国医师协会美容与整形医师分会激光学组. 中国痤疮瘢痕治疗专家共识（2021）[J]. 中华皮肤科杂志, 2021, 54(9): 747-756.
[9]	吴淑辉朱明芳魏露张曦朱亚梦. 石榴皮多酚对金黄地鼠皮脂腺斑及AKT/Sox9信号通路的影响[J]. 中华皮肤科杂志, 2021, 54(8): 705-708.
[10]	储开宇毛荣军王键旋钟敏华莫惠芳. 儿童肢端假性淋巴瘤样血管角皮瘤一例临床病理特征[J]. 中华皮肤科杂志, 2021, 54(8): 709-711.
[11]	应洁雅相文忠宋秀祖. 代谢综合征与皮肤病[J]. 中华皮肤科杂志, 2021, 54(7): 642-645.
[12]	中华医学会皮肤性病学分会银屑病学组中华医学会皮肤性病学分会儿童学组. 中国儿童银屑病诊疗专家共识（2021）[J]. 中华皮肤科杂志, 2021, 54(7): 559-581.
[13]	韩晓锋孙娟徐教生马琳. 儿童脑回状皮脂腺痣14例临床分析[J]. 中华皮肤科杂志, 2021, 54(6): 529-531.
[14]	毕田田管志伟刘欣欣李钦峰. 反射式共聚焦显微镜在儿童疥疮诊疗中的应用[J]. 中华皮肤科杂志, 2021, 54(5): 433-435.
[15]	刘钟胡吉升黄萌陈柳青覃莉周小勇. 小剂量利妥昔单抗联合糖皮质激素治疗儿童落叶型天疱疮一例疗效观察[J]. 中华皮肤科杂志, 2021, 54(5): 436-437.

儿童期痤疮

Childhood acne

PDF

PDF (Mobile)

可视化

摘要/Abstract

引用本文

使用本文

参考文献 31

相关文章 15

Metrics

本文评价

推荐阅读 10