中华皮肤科杂志 ›› 2022, Vol. 55 ›› Issue (3): 246-250.doi: 10.35541/cjd.20210573

• 调查报告 • 上一篇    下一篇

基于两家儿童医院信息系统的儿童银屑病现状调查

王召阳1    陈安薇2    向欣1    罗晓燕2    徐子刚1    王华2    马琳1   

  1. 1国家儿童医学中心  首都医科大学附属北京儿童医院皮肤科，北京  100045；2重庆医科大学附属儿童医院皮肤科，重庆  400014
  • 收稿日期:2021-08-09 修回日期:2021-12-23 发布日期:2022-03-03
  • 通讯作者: 马琳；王华 E-mail:bch_maleen@aliyun.com; huawang63@hotmail.com
  • 基金资助:
    首都医科大学附属北京儿童医院儿童用药专项（YZQN202007）；北京市医院管理局儿科学科协同发展中心专项（XTZD20180502）

An investigation into the current situation of pediatric psoriasis based on the information systems from two children′s hospitals

Wang Zhaoyang1, Chen Anwei2, Xiang Xin1, Luo Xiaoyan2, Xu Zigang1, Wang Hua2, Ma Lin1   

  1. 1Department of Dermatology, Beijing Children′s Hospital, Capital Medical University, National Center for Children′s Health, Beijing 100045, China; 2Department of Dermatology, Children′s Hospital of Chongqing Medical University, Chongqing 400014, China
  • Received:2021-08-09 Revised:2021-12-23 Published:2022-03-03
  • Contact: Ma Lin; Wang Hua E-mail:bch_maleen@aliyun.com; huawang63@hotmail.com
  • Supported by:
    Children′s Medicine Research Project of Beijing Children′s Hospital, Capital Medical University （YZQN202007）; The Special Fund of the Pediatric Medical Coordinated Development Center of Beijing Hospitals Authority （XTZD20180502）

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摘要： 【摘要】 目的 基于两家儿童医院信息系统调查分析儿童银屑病临床特征。方法 利用首都医科大学附属北京儿童医院和重庆医科大学附属儿童医院信息系统，调取2015年1月1日至2019年12月31日确诊的儿童银屑病门诊患者资料进行临床流行病学调查。采用t检验和卡方检验对调查结果进行统计学分析。结果 共纳入5 235例银屑病患儿，男女比例1∶1.08，就诊年龄M（Q1，Q3）为8.37（6.48，10.50）岁，以学龄期最常见；发病年龄为7.57（5.37，9.82）岁。5 235例银屑病患儿中，寻常型3 195例（60.82%），脓疱型281例（5.37%），红皮病型19例（0.36%），关节病型1例（0.02%）。受累部位以躯干部最常见，占87.76%（1 097/1 250），四肢占87.68%（1 096/1 250），头皮占62.56%（782/1 250），面颈部占35.76%（447/1 250）。4 319例（82.50%）治疗方案以外用药为主，177例（3.38%）接受系统治疗，832例（15.89%）应用抗生素治疗。3 497例应用初始治疗方案的患儿中，3 423例（97.88%）可控制，无治疗方案变化，2.12%需要调整治疗方案。结论 两家儿童医院就诊的儿童银屑病患儿发病年龄及就诊年龄均以学龄期为主，临床类型以寻常型最常见；皮损多呈泛发，以躯干及四肢受累最常见，头皮受累不少见；多数儿童银屑病外用药可控制，少数需要系统治疗。

关键词: 银屑病, 儿童, 皮肤表现, 临床方案, 医院信息系统

Abstract: 【Abstract】 Objective To investigate clinical characteristics of pediatric psoriasis based on the information systems from two children′s hospitals. Methods Clinical data on outpatients confirmly diagnosed with pediatric psoriasis were collected from information systems of Beijing Children′s Hospital affiliated to Capital Medical University and Children′s Hospital of Chongqing Medical University from January 1, 2015 to December 31, 2019, and a clinical and epidemiological investigation was conducted. Statistical analysis was carried out by using t test and chi-square test. Results A total of 5 235 children with psoriasis were included, with the ratio of male to female being 1∶1.08. Their age at the clinic visit （M ［Q1, Q3］） was 8.37 （6.48, 10.50） years, and the school-age children were the most common population; their age at onset was 7.57 （5.37, 9.82） years. Among the 5 235 children with psoriasis, there were 3 195 （60.82%） with psoriasis vulgaris, 281 （5.37%） with pustular psoriasis, 19 （0.36%） with erythrodermic psoriasis, and 1 （0.02%） with psoriatic arthritis. The trunk （87.76%, 1 097/1 250） was most frequently affected, followed by the limbs （87.68%, 1 096/1 250）, the scalp （62.56%, 782/1 250）, and the face and neck （35.76%, 477/1 250）. Among the 5 235 patients, 4 319（82.50%） received topical treatments, 177 （3.38%） received systemic treatments, and 832 （15.89%） were treated with antibiotics. Among 3 497 children who received initial treatment regimens, the disease could be controlled in 3 423 （97.88%） without change in treatment regimens, while treatment regimens needed to be adjusted in 2.12%. Conclusions In the two children′s hospitals, most children with psoriasis developed this condition and visited the clinic at school age, and the predominant clinical type was psoriasis vulgaris. Most skin lesions were extensive, and commonly occurred on the trunk and limbs. Scalp involvement was not uncommon. The condition could be controlled by topical treatments in most children with psoriasis, while a few patients needed systemic treatments.

Key words: Psoriasis, Child, Skin manifestations, Clinical protocols, Hospital information systems

引用本文

王召阳 陈安薇 向欣 罗晓燕 徐子刚 王华 马琳. 基于两家儿童医院信息系统的儿童银屑病现状调查[J]. 中华皮肤科杂志, 2022,55(3):246-250. doi:10.35541/cjd.20210573

Wang Zhaoyang, Chen Anwei, Xiang Xin, Luo Xiaoyan, Xu Zigang, Wang Hua, Ma Lin. An investigation into the current situation of pediatric psoriasis based on the information systems from two children′s hospitals [J]. Chinese Journal of Dermatology, 2022, 55(3): 246-250.doi:10.35541/cjd.20210573