关键词: 皮脂腺肿瘤, 脑回状皮脂腺痣, 儿童

Abstract: 【Abstract】 Objective To investigate clinical manifestations and histopathological features of and surgical timing for cerebriform sebaceous nevus. Methods Clinical data were collected from 14 children with cerebriform sebaceous nevus in Beijing Children′s Hospital from June 2014 to December 2019, and clinical manifestations, histopathological features and surgical timing were analyzed retrospectively. Results Of the 14 children, 10 were males and 4 were females. They presented with skin lesions at birth, which were solitary and located on the head and face. These skin lesions gave a cerebriform appearance, with an average diameter of 4.79 cm. Systemic examination showed no abnormality in any children. Histopathological examination showed obvious papillomatous epidermal hyperplasia, large number of mature sebaceous glands and immature hair follicles. All the 14 children underwent surgeries at an average age of 1.94 years. No recurrence was observed during the follow?up of 6 months to 6 years after surgery. Conclusions Cerebriform sebaceous nevus is characterized by a unique cerebriform appearance, mostly occurs on the head and face, and is liable to attract attention, which usually leads to an earlier surgical selection.

Key words: Sebaceous gland neoplasms, Cerebriform sebaceous nevus, Children