Abstract: 【Abstract】 Cutaneous T-cell lymphomas （CTCLs） are malignancies derived from T-cells. The aim of treatment is to control symptoms and achieve long-term remission, and phototherapy and its combined therapy are one of important treatment methods. Phototherapy of CTCLs includes psoralens and ultraviolet A radiation, narrowband ultraviolet B radiation, extracorporeal photochemotherapy, photodynamic therapy, ultraviolet A1 radiation, 308-nm excimer laser and so on. Efficacy of phototherapy is associated with various factors, such as stage of disease, sites of lesions, types of skin photoreaction, etc. In clinical practice, phototherapy involves clearance, consolidation and maintenance phases, but it is still disputed whether maintenance treatment can control the recurrence of CTCLs. Understanding action mechanisms, indications, therapeutic effects and adverse reactions of phototherapy is helpful in selecting the best treatment protocol.

Key words: Lymphoma, T-cell, cutaneous, Ultraviolet therapy, Sezary syndrome, Lymphomatoid papulosis, Mycosis fungoides