Abstract:

Abstract Purpose To study the clinical and pathological features of pediatric eccrine angiomatous hamartoma. Methods The clinical data were collected. The biospy tissues were routinely processed and hematoxylin-exosin staining and immunohistochemistry staining were reviewed microscopically. Results The age of 13 eccrine angiomatous hamartoma was from 2 months to 13 years old (median 5 years old). 7 cases were males and 6 females. 8 cases were congenital lesions. All of 13 cases located in extremities, including 4 cases of finger and palm, 3 foot, 1 arm, 2 knee. All cases occur as macules, plaques or nodules, including 9 cases of single lesion and 4 cases of multiple lesions. Enlargement occurred in All cases and was in concordance with the growth of the patients. The symptoms associated with 13 cases were tenderness (3 cases) and hyperhidrosis (2 cases). Histologically, 13 cases showed increased numbers of eccrine elements and numerous vascular channels in mid to low dermis. Other features included mucin (3 cases), infiltration of adipose tissue (9 cases), nerve hyperplasia (2 cases), thrombosis (3 cases), and hemosiderin (3 cases) as well. Conclusions Eccrine angiomatous hamartoma is an uncommon and benign malformation of skin. It is significant to know its clinical presentation and histopathology.

Key words: Eccrine angiomatous hamartoma, Pathology, Skin