Abstract:

Objective To investigate the expression of AMACR in primary extramammary Paget’s disease. Methods By using immunohistochemical methods, we examined the expression of AMACR on formalin-fixed paraffin-embedded tissue samples from 30 patients with EMPD without associated visceral mallignant noplasms or adnexal carcinoma. Results AMACR was indentified in 17 of 30 cases. The AMACR expression rate of EMPD was 56.7%. Conclusions AMACR can’t be a special maker for distinguish of primary and secondary EMPD.

Key words: AMACR, Pagets disease, extramammary