Abstract: Objective In order to explore the relationship between the annual incidence rate of psoriasis and meteorological factors. Methods An investigation was carried out using single factor correlation analysis, multiple factor regression analysis and correlation analysis among meteorological factors. Results Single factor analysis revealed that the annual incidence of psoriasis showed a significant negative correlation with the mean annual air temperature, atmospheric pressure, relative humidity and whole year rainfall, but a positive correlation with the whole year sunshine time(P<0.05). Multiple factor regression analysis indicated that the air temperature was the main causative factor of the disease(P<0 01). However, it was found by the correlation analysis between factors that the whole year rainfall, sunshine time and mean annual sunshine intensity were strongly associated with the air temperature(P<0.01). Conclusion All the results confirm that the change of meteorological factors plays an important role in the prevalence of psoriasis.

Key words: Psoriasis, Incidenc, Meteorological factors