Chinese Journal of Dermatology ›› 2019, Vol. 52 ›› Issue (5): 357-360.doi: 10.3760/cma.j.issn.0412-4030.2019.05.018

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Relationship between intestinal flora and psoriasis

Wang Liwei, Luo Lingling, Cui Pan′gen, Li Min   

  1. Department of Dermatology, Hospital for Skin Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Received:2018-05-15 Revised:2019-02-27 Online:2019-05-15 Published:2019-04-30
  • Contact: Cui Pan′gen; Li Min E-mail:cuipangen@126.com; drlimin@sina.cn
  • Supported by:
    CAMS Innovation Fund for Medical Sciences (2017-I2M-1-017)

Abstract: 【Abstract】 Psoriasis is a chronic recurrent inflammatory skin disease, and its pathogenesis is still unclear. At present, it is believed that immune, genetic and environmental factors play important roles in the occurrence of psoriasis. More and more studies have indicated that the imbalance of intestinal flora is associated with immune diseases, especially inflammatory bowel disease. The pathogenesis and clinical manifestations of psoriasis are similar to those of inflammatory bowel disease, and psoriasis is proved to be associated with changes in intestinal microbial flora. This review discusses the association between the imbalance of intestinal flora and psoriasis.

Key words: Psoriasis, Imbalance of intestinal flora