Chinese Journal of Dermatology ›› 2019, Vol. 52 ›› Issue (5): 350-353.doi: 10.3760/cma.j.issn.0412-4030.2019.05.016

• Reviews • Previous Articles     Next Articles

MicroRNA and lncRNA in psoriasis

Hu Yu, Chen Min, Gu Heng   

  1. Department of Physical Therapy, Hospital for Skin Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Received:2018-04-20 Revised:2019-01-04 Online:2019-05-15 Published:2019-04-30
  • Contact: Gu Heng E-mail:guheng@aliyun.com
  • Supported by:
    CAMS Innovation Fund for Medical Sciences (CIFMS-2017-I2M-1-017); Graduate Innovation Fund of Peking Union Medical College (2017-1002-2-12)

Abstract: 【Abstract】 Psoriasis is a common chronic inflammatory skin disease, and commonly considered as a T cell?mediated abnormal immune disease with genetic predisposition at present. Recent studies have indicated that microRNA and lncRNA play important roles in occurrence and development of a variety of inflammatory immune diseases. It has been confirmed that microRNA and lncRNA participate in the occurrence of psoriasis by regulating the proliferation and differentiation of keratinocytes, release of inflammatory factors, and angiopoiesis. This review summarizes research advances in roles of microRNA and lncRNA in psoriasis.

Key words: Psoriasis, MicroRNAs, LncRNAs