Abstract: 【Abstract】 Drug eruptions, also referred to as cutaneous adverse drug reactions, are inflammatory skin and mucosal lesions that occur following drug exposure via oral, injectable, inhalational, or other routes. In severe cases, extracutaneous organ involvement may occur and may even lead to death. In recent years, substantial progress has been made in the diagnosis and treatment of drug eruptions. However, existing consensus statements and guidelines in China lack unified standards for systematic, evidence-based clinical management of drug eruptions. To standardize the diagnosis and treatment of drug eruptions, the Chinese Society of Dermatology, the Chinese Society of Allergy, and the China Leprosy Association convened 56 experts to develop this guideline. Based on the latest literature, the guideline was formulated in accordance with the World Health Organization Handbook for Guideline Development and the Grading of Recommendations Assessment, Development, and Evaluation methodology. This guideline provides updated and comprehensive recommendations for the diagnosis, treatment, and preventive management of drug eruptions, with the aim of enhancing clinicians' capacity to recognize drug eruptions, deliver standardized treatment, and implement evidence-based prevention strategies.

Key words: Drug eruptions, Drug-related side effects and adverse reactions, Severe drug eruptions, Diagnostic and treatment guideline