Chinese Journal of Dermatology ›› 2023, e20220388.doi: 10.35541/cjd.20220388

• Reviews • Previous Articles     Next Articles

Evaluation of dermatomyositis complicated by interstitial lung disease based on skin lesions, serum biomarkers and radiological features

Ye Jiaqi1, Chai Weimin2, Zheng Jie1, Cao Hua1   

  1. 1Department of Dermatology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; 2Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
    Corresponding authors: Cao Hua, Email: drcaohua@126.com; Chai Weimin, Email: cwm11394@rjh.com.cn
  • Received:2022-06-01 Revised:2023-08-02 Online:2023-01-05 Published:2023-11-21
  • Contact: Cao Hua; Chai Weimin E-mail:drcaohua@126.com; cwm11394@rjh.com.cn
  • Supported by:
    National Natural Science Foundation of China (81573037, 81872523, 82073432); National Key Clinical Specialty (2012649); Science and Technology Commission of Shanghai Municipality (134119a6100); Clinical Research Plan of Shanghai Hospital Development Center (16CR3084B); Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support (20172009); Shanghai "Rising Stars of Medical Talent" Youth Development Program Outstanding Youth Medical Talents (2019)

Abstract: 【Abstract】 Dermatomyositis is an autoimmune disease mainly involving the skin and muscles, as well as the heart, lungs, and joints, and it may even be complicated by malignant tumors. Among these complications, interstitial lung disease (ILD) is of particular concern. Because of the urgent onset and rapid progress, ILD is hard to diagnose at the early stage, leading to treatment delay. Furthermore, ILD is the common cause of death in patients with dermatomyositis. This review summarizes types of skin lesions, serum biomarkers and radiological features to evaluate the risk, severity and prognosis of dermatomyositis complicated by ILD.

Key words: Dermatomyositis, Lung disease, interstitial, Skin lesion, Biomarker, Radiological technology