Chinese Journal of Dermatology ›› 2022, Vol. 55 ›› Issue (11): 1008-1013.doi: 10.35541/cjd.20220005

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Evolution of diagnostic criteria for clinically amyopathic dermatomyositis

Cao Hua, Zheng Jie    

  1. Department of Dermatology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Received:2022-01-04 Revised:2022-04-19 Online:2022-11-15 Published:2022-11-03
  • Contact: Zheng Jie
  • Supported by:
    National Natural Science Foundation of China (81573037, 81872523, 82073432); National Clinical Key Subject Construction Project (2012649); Shanghai Municipal Science and Technology Commission Medical Guide Project (134119a6100); Clinical Research Plan of Shanghai Shen-kang Hospital Development Center (16CR3084B); Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support(20172009); Shanghai "Rising Stars of Medical Talent" Youth Development Program-Outstanding Youth Medical Talents (2019)

Abstract: 【Abstract】 At present, the Bohan and Peter criteria are the most widely used criteria for the diagnosis of dermatomyositis, which require patients to meet at least 2 criterion items for myositis in addition to typical skin lesions before the diagnosis of dermatomyositis. Clinically amyopathic dermatomyositis(CADM) has been excluded due to the absence of myositis manifestations, resulting in a lack of early studies on this type of dermatomyositis, and little attention has been paid to it by clinicians. In addition, the diagnosis of CADM depends on the understanding of skin lesions and their histopathological manifestations. Because of atypical early skin lesions, CADM is often misdiagnosed as rosacea, seborrheic dermatitis, lupus erythematosus and other diseases, which affects the early diagnosis, treatment and prognosis of patients. This article summarizes the evolution of diagnostic criteria for CADM, in order to promote its early recognition and diagnosis, and also to provide a basis for future clinical research.

Key words: Dermatomyositis, Diagnosis, Clinically amyopathic dermatomyositis, Diagnostic criteria