基于代谢组学探究特应性疾病的研究进展

doi:10.35541/cjd.20220366

Abstract

Abstract: 【Abstract】 Atopic diseases are a series of allergic diseases, including atopic dermatitis, allergic asthma, and allergic rhinitis, etc., with complex pathogenesis. Metabolomics studies focus on endogenous small-molecule compounds at the end of different metabolic pathways, which can directly reflect the human body′s functional state. In recent years, a large number of metabolomic studies have shown various abnormal biochemical metabolic pathways in patients with atopic diseases, specifically manifesting as aberrantly high levels of some amino acids, unsaturated fatty acids, and microbial metabolites. This review summarizes the progress in metabolomics research on atopic diseases in recent years, to further reveal the potential pathogenesis of atopic diseases.

Key words: Dermatitis, atopic, Rhinitis, allergic, Asthma, Metabolomics, Biomarkers, Differential metabolites, Phenotype

Chen Zhu, Dong Liping, Xiao Fengli, . Research progress in atopic diseases from the perspective of metabolomics[J]. Chinese Journal of Dermatology,2024,e20220366. doi:10.35541/cjd.20220366

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Research progress in atopic diseases from the perspective of metabolomics

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