Abstract: 【Abstract】 Virus infection is one of the common complications of pemphigus. In recent years, related studies on pemphigus complicated by virus infection have mainly focused on the herpes simplex virus （HSV）. Studies have shown that HSV infection can affect the course of disease, therapeutic effect, and even the morphology of skin lesions in patients with pemphigus. However, due to large differences in sample sizes and test methods, the incidence and clinical characteristics of HSV infection in patients with pemphigus markedly differ among different studies. This review summarizes the incidence and clinical characteristics of pemphigus complicated by HSV infection, aiming to improve clinicians′ understanding of the disease and provide a basis for its diagnosis and treatment.

Key words: Pemphigus, Herpesvirus 1, human, Herpesvirus 2, human, Disease attributes