Chinese Journal of Dermatology ›› 2022, Vol. 55 ›› Issue (6): 545-548.doi: 10.35541/cjd.20200248

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Pemphigus complicated by herpes simplex virus infection

Zhang Hanmei, Feng Suying   

  1. Department of Dermatology, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Received:2020-03-12 Revised:2020-06-15 Online:2022-06-15 Published:2022-06-02
  • Contact: Feng Suying
  • Supported by:
    CAMS Innovation Fund for Medical Sciences(CIFMS-2017-I2M-1-017)

Abstract: 【Abstract】 Virus infection is one of the common complications of pemphigus. In recent years, related studies on pemphigus complicated by virus infection have mainly focused on the herpes simplex virus (HSV). Studies have shown that HSV infection can affect the course of disease, therapeutic effect, and even the morphology of skin lesions in patients with pemphigus. However, due to large differences in sample sizes and test methods, the incidence and clinical characteristics of HSV infection in patients with pemphigus markedly differ among different studies. This review summarizes the incidence and clinical characteristics of pemphigus complicated by HSV infection, aiming to improve clinicians′ understanding of the disease and provide a basis for its diagnosis and treatment.

Key words: Pemphigus, Herpesvirus 1, human, Herpesvirus 2, human, Disease attributes