| ［1］ |
Bieber T, D′Erme AM, Akdis CA, et al. Clinical phenotypes and endophenotypes of atopic dermatitis: where are we, and where should we go?［J］. J Allergy Clin Immunol, 2017,139（4S）:S58⁃S64. doi: 10.1016/j.jaci.2017.01.008.
|
| ［2］ |
Tanei R. Atopic dermatitis in the elderly［J］. Inflamm Allergy Drug Targets, 2009,8（5）:398⁃404. doi: 10.2174/187152811090 8050398.
|
| ［3］ |
Sandström Falk MH, Faergemann J. Atopic dermatitis in adults: does it disappear with age?［J］. Acta Derm Venereol, 2006,86（2）:135⁃139. doi: 10.2340/00015555⁃0040.
|
| ［4］ |
Vakharia PP, Silverberg JI. Adult⁃onset atopic dermatitis: characteristics and management［J］. Am J Clin Dermatol, 2019,20（6）:771⁃779. doi: 10.1007/s40257⁃019⁃00453⁃7.
|
| ［5］ |
Williamson S, Merritt J, De Benedetto A. Atopic dermatitis in the elderly: a review of clinical and pathophysiological hallmarks［J］. Br J Dermatol, 2020,182（1）:47⁃54. doi: 10.1111/bjd.17896.
|
| ［6］ |
Zhou L, Leonard A, Pavel AB, et al. Age⁃specific changes in the molecular phenotype of patients with moderate⁃to⁃severe atopic dermatitis［J］. J Allergy Clin Immunol, 2019,144（1）:144⁃156. doi: 10.1016/j.jaci.2019.01.015.
|
| ［7］ |
Kawashima T, Kobayashi S, Miyano M, et al. Senile type atopic dermatitis［J］. Nihon Hifuka Gakkai Zasshi, 1989,99（10）:1095⁃1103.
|
| ［8］ |
Muto T, Hsieh SD, Sakurai Y, et al. Prevalence of atopic dermatitis in Japanese adults［J］. Br J Dermatol, 2003,148（1）:117⁃121. doi: 10.1046/j.1365⁃2133.2003.05092.x.
|
| ［9］ |
Takeuchi S, Esaki H, Furue M. Epidemiology of atopic dermatitis in Japan［J］. J Dermatol, 2014,41（3）:200⁃204. doi: 10.1111/1346⁃8138.12331.
|
| ［10］ |
Tanei R, Katsuoka K. Clinical analyses of atopic dermatitis in the aged［J］. J Dermatol, 2008,35（9）:562⁃569. doi: 10.1111/j.1346⁃8138.2008.00524.x.
|
| ［11］ |
Tanei R, Hasegawa Y. Atopic dermatitis in older adults: a viewpoint from geriatric dermatology［J］. Geriatr Gerontol Int, 2016,16 Suppl 1:75⁃86. doi: 10.1111/ggi.12771.
|
| ［12］ |
Wang S, Zhu R, Gu C, et al. Distinct clinical features and serum cytokine pattern of elderly atopic dermatitis in China［J］. J Eur Acad Dermatol Venereol. 2020. doi: 10.1111/jdv.16346.
|
| ［13］ |
Lee HH, Patel KR, Singam V, et al. A systematic review and meta⁃analysis of the prevalence and phenotype of adult⁃onset atopic dermatitis［J］. J Am Acad Dermatol, 2019,80（6）:1526⁃1532.e7. doi: 10.1016/j.jaad.2018.05.1241.
|
| ［14］ |
Yatagai T, Shimauchi T, Yamaguchi H, et al. Sensitive skin is highly frequent in extrinsic atopic dermatitis and correlates with disease severity markers but not necessarily with skin barrier impairment［J］. J Dermatol Sci,2018,89（1）:33⁃39. doi: 10.1016/j.jdermsci.2017.10.011.
|
| ［15］ |
Fölster⁃Holst R, Pape M, Buss YL, et al. Low prevalence of the intrinsic form of atopic dermatitis among adult patients［J］. Allergy, 2006,61（5）:629⁃632. doi: 10.1111/j.1398⁃9995.2006. 01076.x.
|
| ［16］ |
He H, Li R, Choi S, et al. Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis［J］. Ann Allergy Asthma Immunol, 2020,124（1）:70⁃78. doi: 10.1016/j.anai.2019.10.013.
|
| ［17］ |
Katayama I, Aihara M, Ohya Y, et al. Japanese guidelines for atopic dermatitis 2017［J］. Allergol Int, 2017,66（2）:230⁃247. doi: 10.1016/j.alit.2016.12.003.
|
| ［18］ |
Liu P, Zhao Y, Mu ZL, et al. Clinical features of adult/adolescent atopic dermatitis and Chinese criteria for atopic dermatitis［J］. Chin Med J （Engl）, 2016,129（7）:757⁃762. doi: 10.4103/0366⁃6999.178960.
|
| ［19］ |
Brunner PM, Guttman⁃Yassky E, Leung DY. The immunology of atopic dermatitis and its reversibility with broad⁃spectrum and targeted therapies［J］. J Allergy Clin Immunol, 2017,139（4S）:S65⁃S76. doi: 10.1016/j.jaci.2017.01.011.
|
| ［20］ |
Ahn C, Huang W. Clinical presentation of atopic dermatitis［J］. Adv Exp Med Biol, 2017,1027:39⁃46. doi: 10.1007/978⁃3⁃319⁃64804⁃0_4.
|
| ［21］ |
Seegräber M, Srour J, Walter A, et al. Dupilumab for treatment of atopic dermatitis［J］. Expert Rev Clin Pharmacol, 2018,11（5）:467⁃474. doi:10.1080/17512433.2018.1449642.
|
