黑素核在黑素转运与降解中的作用

doi:10.35541/cjd.20190198

Abstract

Abstract: 【Abstract】 Skin color is regulated by the change of melanin. Previous studies have shown that there are 4 modes of melanin transfer, including exocytosis-endocytosis, shedding-phagocytosis, cell phagocytosis and membrane fusion, and melanosomes are the main carrier of melanin transfer. Recent studies have shown that melanocores depending on the exocytosis-endocytosis pathway play an important role in melanin transfer. This review summarizes the melanocyte exocytosis and keratinocyte endocytosis processes in melanocore transfer, as well as the melanocore degradation process in keratinocytes after melanocore transfer, providing a new therapeutic direction for refractory pigmented diseases.

Key words: Melanosomes, Melanocytes, Keratinocytes, Endocytosis, Melanocore

Geng Qingwei, Song Xiuzu. Role of melanocores in melanin transfer and degradation[J]. Chinese Journal of Dermatology, 2020, 53(8): 658-660.doi:10.35541/cjd.20190198

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Role of melanocores in melanin transfer and degradation

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