长链非编码RNA在婴幼儿血管瘤中的研究进展

doi:10.35541/cjd.20210400

中华皮肤科杂志 ›› 2023, Vol. 56 ›› Issue (12): 1173-1176.doi: 10.35541/cjd.20210400

长链非编码RNA在婴幼儿血管瘤中的研究进展

谢德琼¹ 杨开颖¹ 杨旸¹ 陈思源² 吉毅¹

¹四川大学华西医院小儿外科，成都 610041；²四川大学华西医院重症医学科，成都 610041

收稿日期:2021-05-24 修回日期:2021-10-27 发布日期:2023-12-05
通讯作者: 吉毅 E-mail:jijiyuanyuan@163.com
基金资助:
国家自然科学基金（81401606、81400862）；四川大学优秀青年学者基金（2015SU04A15）；四川省科技厅重点研发项目（2019YFS0322）;四川大学华西医院学科卓越发展1·3·5工程项目（2019HXFH056、2020HXFH048、ZYJC21060）

Long non-coding RNAs in infantile hemangioma

Xie Deqiong¹, Yang Kaiying¹, Yang Yang¹, Chen Siyuan², Ji Yi¹

¹Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu 610041, China; ²Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China

Received:2021-05-24 Revised:2021-10-27 Published:2023-12-05
Contact: Ji Yi E-mail:jijiyuanyuan@163.com
Supported by:
National Natural Science Foundation of China（81401606, 81400862）; Science Foundation for Excellent Youth Scholars of Sichuan University（2015SU04A15）; Key Project in the Science & Technology Program of Sichuan Province（2019YFS0322）; The 1·3·5 Project for Disciplines of Excellence, West China Hospital of Sichuan University （2019HXFH056, 2020HXFH048, ZYJC21060）

摘要/Abstract

摘要： 【摘要】长链非编码RNA（lncRNA）可通过调控染色体重塑、基因转录及蛋白质翻译等影响细胞增殖、迁移及血管生成等多种生物学过程。本文综述近期lncRNA在婴幼儿血管瘤中的研究进展，总结lncRNA在婴儿血管瘤发生发展中的作用，以期为其治疗提供新方向。

关键词: 血管瘤, 婴儿, RNA, 未翻译, 长链非编码RNA, 发病机制

Abstract: 【Abstract】 Long non-coding RNAs （lncRNAs） can affect various biological processes, such as cell proliferation, migration, and angiogenesis, by regulating chromosome remodeling, gene transcription or protein translation. This review summarizes recent research progress in the role of lncRNAs in the occurrence and development of infantile hemangioma, in order to provide new directions for treatment of infantile hemangioma.

Key words: Hemangioma, Infant, RNA, untranslated, Long noncoding RNA, Pathogenesis

谢德琼杨开颖杨旸陈思源吉毅. 长链非编码RNA在婴幼儿血管瘤中的研究进展[J]. 中华皮肤科杂志, 2023,56(12):1173-1176. doi:10.35541/cjd.20210400

Xie Deqiong, Yang Kaiying, Yang Yang, Chen Siyuan, Ji Yi. Long non-coding RNAs in infantile hemangioma[J]. Chinese Journal of Dermatology, 2023, 56(12): 1173-1176.doi:10.35541/cjd.20210400

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长链非编码RNA在婴幼儿血管瘤中的研究进展

Long non-coding RNAs in infantile hemangioma

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