中华皮肤科杂志 ›› 2021, Vol. 54 ›› Issue (8): 738-741.doi: 10.35541/cjd.20191024

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伊马替尼引起的皮肤不良反应

杨敏    常建民   

  1. 北京医院皮肤科  国家老年医学中心  中国医学科学院老年医学研究院，北京  100730
  • 收稿日期:2019-10-23 修回日期:2020-07-07 发布日期:2021-08-02
  • 通讯作者: 常建民 E-mail:changjm0417@126.com

Imatinib-induced cutaneous adverse reactions

Yang Min, Chang Jianmin   

  1. Department of Dermatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China
  • Received:2019-10-23 Revised:2020-07-07 Published:2021-08-02
  • Contact: Chang Jianmin E-mail:changjm0417@126.com

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摘要： 【摘要】 甲磺酸伊马替尼是治疗慢性髓性白血病和恶性胃肠道间质肿瘤的一线用药，其皮肤黏膜不良反应的发生率较高。作者通过复习国内外文献描述该药导致的各种皮肤黏膜症状，并总结其发病机制和治疗对策，旨在帮助皮肤科医生提高对该药皮肤黏膜不良反应的认识，给予及时诊治。

关键词: 药物毒性, 皮肤, 黏膜, 伊马替尼

Abstract: 【Abstract】 Imatinib mesylate is the first-line drug for the treatment of chronic myeloid leukemia and malignant gastrointestinal stromal tumors, with a high incidence of mucocutaneous adverse reactions. Based on Chinese and international literature, the authors comprehensively describe various mucocutaneous symptoms induced by imatinib mesylate, and summarize their pathogenesis and management strategies, aiming to help dermatologists improve their understanding of mucocutaneous adverse reactions to this drug, and provide timely diagnosis and treatment.

Key words: Drug toxicity, Skin, Mucous membrane, Imatinib

引用本文

杨敏 常建民. 伊马替尼引起的皮肤不良反应[J]. 中华皮肤科杂志, 2021,54(8):738-741. doi:10.35541/cjd.20191024

Yang Min, Chang Jianmin. Imatinib-induced cutaneous adverse reactions[J]. Chinese Journal of Dermatology, 2021, 54(8): 738-741.doi:10.35541/cjd.20191024