中华皮肤科杂志 ›› 2010, Vol. 43 ›› Issue (7): 517-519.

• 皮肤科教程 • 上一篇    

表皮通透屏障功能对皮肤的调节作用及意义

蔄茂强1,宋顺鹏2,侯麦花3,Peter M Elias4   

  1. 1. Dermatology,University of California San Frnacisco and NCIRE
    2.
    3. 南京医科大学第一附属医院皮肤科
    4. Dermatology, UCSF, USA
  • 收稿日期:2009-09-28 修回日期:2010-02-25 出版日期:2010-07-15 发布日期:2010-07-13
  • 通讯作者: 蔄茂强 E-mail:maoqiangman@hotmail.com
  • 基金资助:

    美国公共卫生研究院

Regulatory effect of epidermal permeability barrier function on skin and its implication

  • Received:2009-09-28 Revised:2010-02-25 Online:2010-07-15 Published:2010-07-13
  • Contact: Mao-Qiang Man E-mail:maoqiangman@hotmail.com
  • Supported by:

    US National Institutes of Health

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摘要：

表皮通透屏障功能除调节水分经表皮进出机体外，还对皮肤的其他生物功能如炎症、表皮增生、pH及离子的分布等也具有重要地调节作用。而且，维持表皮通透屏障功能在最佳水平有利于预防某些皮肤病的发生；改善皮肤屏障功能有助于某些皮肤病的治疗。

关键词: 表皮通透屏障功能, 增生, 分化, 炎症, 皮肤

Abstract:

In addition to regulating water in and out of the body, epidermal permeability barrier function also plays important roles in regulating other cutaneous functions including cutaneous inflammation, epidermal proliferation, pH and ions, etc. Therefore, maintaining epidermal permeability barrier function at optimal level could prevent onset of some skin diseases; improving epidermal permeability barrier function could have beneficial effects in treating some skin disorders.

Key words: epidermal permeability barrier function, proliferation, differentiation, inflammation, skin.