中华皮肤科杂志 ›› 2010, Vol. 43 ›› Issue (7): 463-466.

• 论著 • 上一篇    下一篇

中国六省市白癜风流行病学调查

王晓艳1,王婷琳2,周城1,沈佚葳3,丁晓岚4,刘盈5,彭光辉6,周俊娥4,薛树旗7,王仁利3,孟雪梅8,白云花9,刘青3,李航杜娟4,张建中4   

  1. 1. 北京大学人民医院
    2. 北京民航总医院皮肤科
    3.
    4. 北京大学人民医院皮肤科
    5. 北京市儿童医院皮肤科
    6. 北京市石景山首都钢铁总医院皮肤科
    7. 太钢迎新医院
    8. 河北省廊坊市石油天然气集团公司中心医院
    9. 内蒙古海拉尔市呼伦贝尔盟人民医院
  • 收稿日期:2009-12-14 修回日期:2010-01-11 出版日期:2010-07-15 发布日期:2010-07-13
  • 通讯作者: 王晓艳 E-mail:wxy100083@163.com

Prevalence of vitiligo in China: an epidemiological survey in 6 provinces

  • Received:2009-12-14 Revised:2010-01-11 Online:2010-07-15 Published:2010-07-13
  • Contact: Wang XiaoYan E-mail:wxy100083@163.com

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摘要：

目的 通过多地区、大样本流行病学调查，获得中国白癜风患病情况的基本资料。方法 在我国6个省、自治区中各选择1个城市作为调查点，采取整群抽样方法。所有被调查者填写问卷和接受皮肤科医师检查。调查数据录入EpiData数据库，运用SPSS 13.0软件进行统计学分析。结果 共抽样调查19 974例，有效问卷17 345份，应答率86.84%。发现白癜风患者122例，总患病率0.70%，标化患病率为0.56%。其中男性患者75例，患病率为0.95%，标化患病率为0.69%，女性患者47例，患病率为0.50%，标化患病率为0.45%。男性患病率较女性高，差异具有统计学意义（P < 0.01）。患病率随着年龄增长呈上升趋势，60 ~ 69岁、≥70岁组患病率最高。0 ~ 19岁初次发病的人数占21.85%，20 ~ 49岁初次发病的人数占47.05%。临床分型中限局型最常见（36.06%），节段型最少见（2.46%）。白癜风患者家族史阳性率为9.84%，社区人群为1.31%，差异具有统计学意义（P < 0.01）。31.97%的患者认为白癜风对生活质量造成影响。结论 中国六省市白癜风标化患病率为0.56%。男性患病率高于女性。

关键词: 白癜风, 流行病学调查, 患病率, 中国大陆

Abstract:

Objective To investigate the prevalence of vitiligo in China through a multi-center and large-population epidemiological survey. Methods A community-based survey was conducted in 6 cities from 6 provinces. Cluster sampling method was used. Subjects were required to fulfill the self-report questionnaires and received physical examination by dermatologists. EpiData and SPSS11.5 were utilized for statistical analysis. Results Totally, 19 974 patients participated in this study, and 17 345 valid questionnaires were retrieved with a return rate of 86.84%. Of them, 122 were found to have vitiligo. The prevalence and standardized prevalence of vitiligo was 0.70% and 0.56% in all patients, 0.95% （75） and 0.69% in male patients and 0.50% （47） and 0.45% in female patients, respectively. A significant elevation was observed in the prevalence of vitiligo in males than in females （P < 0.01）. The prevalence of vitiligo was increased with age and peaked in patients aging from 60 to 69 years and those over 70 years. The age at onset of vitiligo varied from 0 to 19 years in 21.85% of these patients, from 20 to 49 years in 47.05%. The most common type was focal vitiligo, which accounted for 36.06%, while the rarest type was segmental type（2.46%）. The positivity rate of family history of vitiligo was 9.84% in patients and 1.31% in community population （P < 0.01）. About 31.97% of the patients complained of negative influence of vitiligo on quality of life. Conclusions The standardized prevalence of vitiligo is 0.56% in 6 provinces from China. Males seem to have a higher prevalence of vitiligo than females.

Key words: vitiligo, survey, prevalence, China mainland