中华皮肤科杂志 ›› 2019, Vol. 52 ›› Issue (4): 279-282.doi: 10.3760/cma.j.issn.0412-4030.2019.04.013

• 综述 • 上一篇    下一篇

富血小板血浆在皮肤科中的应用进展

侯晓媛    鲁严   

  1. 南京医科大学第一附属医院皮肤科  210029
  • 收稿日期:2018-04-03 修回日期:2018-08-06 出版日期:2019-04-15 发布日期:2019-04-01
  • 通讯作者: 鲁严 E-mail:luyan6289@163.com

Application of platelet-rich plasma in dermatology

Hou Xiaoyuan, Lu Yan   

  1. Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
  • Received:2018-04-03 Revised:2018-08-06 Online:2019-04-15 Published:2019-04-01
  • Contact: Lu Yan E-mail:luyan6289@163.com

摘要: 【摘要】 富血小板血浆是离心自体全血后得到的血小板浓缩液,其最佳工作浓度为全血中血小板计数的4~7倍。血小板与凝血酶或氯化钙接触后被激活,可释放多种生长因子,具有止血、促进组织愈合、增强血管生成等作用,被认为是一种较低成本且安全的治疗方式,从而被广泛地应用于软组织和硬组织的创伤修复中。其在皮肤科中也得到广泛的应用,涉及脱发、皮肤年轻化、瘢痕修复、创面愈合等多个领域。本篇综述了富血小板血浆在皮肤科中的应用进展。

关键词: 富血小板血浆, 秃发, 白癜风, 萎缩纹, 瘢痕, 伤口愈合, 年轻化

Abstract: 【Abstract】 Platelet-rich plasma (PRP) is a platelet concentrate isolated from the autologous whole blood after centrifugation, and its optimal working concentration is 4 - 7 times that of the blood platelet count in the whole blood. After the activation by thrombin or calcium chloride, platelets can release various growth factors, which can promote hemostasis, wound healing and angiogenesis. Considered as a kind of low-cost and safe therapy, it has been widely applied to the repair of soft tissue and hard tissue injuries. PRP has also been widely applied to dermatology, including hair loss, skin rejuvenation, scar repair and wound healing. This review summarizes the application of PRP in dermatology.

Key words: Platelet-rich plasma, Alopecia, Vitiligo, Striae distensae, Cicatrix, Wound healing, Rejuvenation