中华皮肤科杂志 ›› 2003, Vol. 36 ›› Issue (9): 493-495.

• 论著 • 上一篇    下一篇

超脉冲CO2激光结合自体表皮移植治疗白癜风

余文林, 刘春利, 曾海玲, 曾东   

  1. 广州军区广州总医院激光整形美容中心, 510010
  • 收稿日期:2002-10-08 出版日期:2003-09-15 发布日期:2003-09-15

Combined Therapy of Ultrapulse CO2 Laser with Autologous Epidermal Grafting in Vitiligo

YU Wen-lin, LIU Chun-li, ZENG Hai-ling, ZENG Dong   

  1. Guangzhou General Hospital of Guangzhou Military Region, Guangzhou 510010, China
  • Received:2002-10-08 Online:2003-09-15 Published:2003-09-15

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摘要： 目的 探讨CO2激光结合自体表皮移植治疗白癜风的临床疗效。方法 对1605例白癜风患者进行自体表皮移植治疗,共植皮30660片,其中局限型782例12151片,节段型319例8221片,泛发型226例7376片,散发型278例2912片。采用发疱取皮法,受皮区采用CO2激光汽化创面形成,治疗8周后判断疗效。结果 治愈率79.04%,有效率13.17%,总有效率92.21%。以局限型和散发型效果最好,泛发型效果较差,身体各部以面部效果最佳,胸背部次之,眉区及发际最差。结论 超脉冲CO2激光辅助自体表皮移植治疗白癜风具有操作简单、方便,手术时间短,出血少,皮片易存活,治愈率高的优点,值得临床推广。

关键词: 白癜风, 移植, 激光

Abstract: Objective To observe the clinical efficacy and safety of ultrapulse CO2 laser-assisted autologous epidermal grafting for the treatment of vitiligo.Methods 1605 patients with 30660 skin grafts were treated by CO2 laser-assisted autologous epidermal grafting.Among them,782 patients had localized vitiligo,319 segmental,226 general and 278 scattered.Epidermal grafts were harvested with negative pressure blistering method from normally pigmented skin,and recipient areas were prepared with a ultrapulse CO2 laser.The curative effect was evaluated 8 weeks later.Results 79.04% of the lesions were cured completely,and total response rate was 92.21%,with better effect in localized and scattered lesions than in other lesions.The best results were shown in face,while the worst results shown in brow and hairline lesions.Conclusions The advantage of combined therapy of CO2 laser with autologous epidermal grafting in vitiligo is of easy performance,convenience,high response rate,which is worthy of large scale application.

Key words: Vitiligo, Transplantation, Lasers