中华皮肤科杂志 ›› 1995, Vol. 28 ›› Issue (2): 75-76.

• 论著 • 上一篇    下一篇

银屑病患者人巨细胞病毒感染的研究

刘成玉1, 王桂芝2, 罗兵3, 谭润鸾1, 赵旭传4   

  1. 1. 青岛医学院诊断学教研室, 266021;
    2. 青岛医学院皮肤病研究所, 266021;
    3. 青岛医学院微生物学教研室, 266021;
    4. 青岛市立医院皮肤科
  • 收稿日期:1994-07-28 修回日期:1994-09-24 出版日期:1995-04-15 发布日期:1995-04-15

Study on Human Cytomegalovirus Infection in Patients with Psoriasis

Liu Chengyu1, Wang Guizhi2, Luo Bing3   

  1. Department of Diagnostics, Qingdao Aledical College, Qingdao 266021
  • Received:1994-07-28 Revised:1994-09-24 Online:1995-04-15 Published:1995-04-15

PDF (PC)

368

赞

摘要： 用高敏感性酶联免疫吸附法和多聚酶链反应(PCR)技术分别检测了86例银屑病患者血清特异性人巨细胞病毒(HCMV)-IgM和HCMV-IgA及尿HCMV-DNA的变化.结果显示,银屑病患者活动性HCMV感染率和尿HCMV-DNA阳性率分别为55.8%和24.4%,而对照组则为4.0%和0,两组相比有显着性意义(P<0.001).提示活动性HCMV感染与银屑病有一定关系.

关键词: 银屑病, 巨细胞病毒

Abstract: IgM and IgA antibodies against human cytomegalovirus (HCMV) and urine HCMV-deoxyribonucleic acid (HCMV-DNA) were examined in the serum and urine respectively from 86 patients with psoriasis by using enzymewlinked immunosorbant assay (ELISA) and polymerase chain reaction (PCR).Active HCMV infection and positive rate of HCMV-DNA in the urine were found in 55.8% and 24.4% of patients respectively, but the rates were only 4.0% and 0 in normal subjects (P<0.001).The results indicate that psoriasis is related to active infection of HCMV.

Key words: Psoriasis, Cytomegaloviruses