[开放获取]    外泌体在感染与炎症性皮肤病中的应用与展望

doi:10.35541/cjd.20240148

中华皮肤科杂志 ›› 2025, e20240148.doi: 10.35541/cjd.20240148

[开放获取] 外泌体在感染与炎症性皮肤病中的应用与展望

金哲高冬

烟台毓璜顶医院皮肤科，烟台 264003

收稿日期:2024-03-21 修回日期:2025-05-08 发布日期:2025-09-23
通讯作者: 高冬 E-mail:13385351257@163.com

Application and prospect of exosomes in infection and inflammatory skin diseases

Jin Zhe, Gao Dong

Department of Dermatology, Yuhuangding Hospital, Yantai 264003, Shandong, China

Received:2024-03-21 Revised:2025-05-08 Published:2025-09-23
Contact: Gao Dong E-mail:13385351257@163.com

摘要/Abstract

摘要： 【摘要】外泌体（exosomes）是种几乎所有细胞都可分泌的膜囊泡，可携带运输各种细胞因子、遗传物质信息等成分，参与调节机体众多生理和病理功能。外泌体在多个领域吸引了众多关注，目前皮肤科相关研究多集中在伤口愈合、胶原再生、瘢痕改善、血管再生等方面。鉴于外泌体在炎症性皮肤病及皮肤感染中展现出重要的发展潜力，本文综述外泌体研究进展，特别是在银屑病、特应性皮炎、增生性瘢痕、皮肤感染等疾病中的治疗作用。

关键词: 外泌体, 皮炎, 特应性, 银屑病, 皮炎, 接触性, 皮肤炎症, 皮肤感染

Abstract: 【Abstract】 Exosomes are membrane vesicles secreted by almost all cells and can carry a variety of components, including cytokines and genetic material, involved in regulating numerous physiological and pathological functions of the body. Exosomes have attracted considerable attention in various fields, and dermatological research has primarily focused on areas such as wound healing, collagen regeneration, scar improvement, and angiogenesis. Given the significant potential of exosomes in the development of treatments for inflammatory skin diseases and skin infections, this review summarizes the progress of exosome research, particularly their therapeutic roles in diseases such as psoriasis, atopic dermatitis, hypertrophic scars, and skin infections.

Key words: Exosome, Dermatitis, atopic, Psoriasis, Dermatitis, contact, Cutaneous inflammation, Skin infection

金哲高冬. [开放获取] 外泌体在感染与炎症性皮肤病中的应用与展望[J]. 中华皮肤科杂志, 2025,e20240148. doi:10.35541/cjd.20240148

Jin Zhe, Gao Dong. Application and prospect of exosomes in infection and inflammatory skin diseases[J]. Chinese Journal of Dermatology,2025,e20240148. doi:10.35541/cjd.20240148

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[开放获取] 外泌体在感染与炎症性皮肤病中的应用与展望

Application and prospect of exosomes in infection and inflammatory skin diseases

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