中华皮肤科杂志 ›› 2024, Vol. 57 ›› Issue (3): 275-278.doi: 10.35541/cjd.20230141

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卡波西肉瘤相关疱疹病毒鉴定与分型研究进展

吴澄宇1    王鹏2    康晓静2   

  1. 1新疆医科大学研究生学院,乌鲁木齐  830001;2新疆维吾尔自治区人民医院皮肤性病科 新疆皮肤病临床医学研究中心  新疆皮肤病研究重点实验室,乌鲁木齐  830001
  • 收稿日期:2023-03-13 修回日期:2023-06-23 发布日期:2024-03-04
  • 通讯作者: 康晓静 E-mail:drkangxj666@163.com
  • 作者简介:9月份前出录用通知
  • 基金资助:
    新疆维吾尔自治区自然科学基金(2022D01D23、2020D01C126)

Identification and typing of Kaposi′s sarcoma-associated herpesvirus

Wu Chengyu1, Wang Peng2, Kang Xiaojing2   

  1. 1Graduate School of Xinjiang Medical University, Urumqi 830001, China; 2Department of Dermatology and Venereology, People′s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Clinical Research Center for Dermatologic Diseases, Xinjiang Key Laboratory of Dermatology Research(XJYS1707), Urumqi 830001, China
  • Received:2023-03-13 Revised:2023-06-23 Published:2024-03-04
  • Contact: Kang Xiaojing E-mail:drkangxj666@163.com
  • Supported by:
    Natural Science Foundation of Xinjiang Uygur Autonomous Region of China(2022D01D23、2020D01C126)

摘要: 【摘要】 卡波西肉瘤相关疱疹病毒(KSHV)可导致肿瘤,其编码的致瘤蛋白参与多种肿瘤的发生发展。病毒感染呈多样性,感染率和分型在不同地区、人群中均有差异,不同的病毒亚型在不同疾病中的表现亦存在差异,精准的KSHV鉴定技术和分型方法将加快临床诊断。KSHV的鉴定及分型对于理解病毒的分子生物学特性、制定精准的防治策略以及促进相关肿瘤的研究都具有重要意义。

关键词: 疱疹病毒8型, 人, 基因检测, 免疫学试验, 分子流行病学

Abstract: 【Abstract】 Kaposi′s sarcoma-associated herpesvirus(KSHV) is a cancer-causing virus, and its encoded oncoproteins are involved in the occurrence and development of many tumors. KSHV infections are diverse, and infection rates and typing vary in different regions and populations. Various virus subtypes also exhibit different performances in different diseases. Accurate KSHV identification technology and rapid typing methods will accelerate clinical diagnosis. The identification and typing of KSHV are of great significance for understanding molecular biological characteristics of the virus, formulating new strategies for precise prevention and treatment, and promoting research progress in related tumors.

Key words: Herpesvirus 8, human, Genetic testing, Immunologic tests, Molecular epidemiology

引用本文

吴澄宇 王鹏 康晓静. 卡波西肉瘤相关疱疹病毒鉴定与分型研究进展[J]. 中华皮肤科杂志, 2024,57(3):275-278. doi:10.35541/cjd.20230141

Wu Chengyu, Wang Peng, Kang Xiaojing. Identification and typing of Kaposi′s sarcoma-associated herpesvirus[J]. Chinese Journal of Dermatology, 2024, 57(3): 275-278.doi:10.35541/cjd.20230141