中华皮肤科杂志 ›› 2022, e20220208.doi: 10.35541/cjd.20220208

• 综述 • 上一篇    

【开放获取】银屑病发病机制与微生物菌群相关性研究进展

薛天萍1    陆振中1    王洪生2   

  1. 1苏州市吴中人民医院皮肤科,苏州  215128;2中国医学科学院、北京协和医学院皮肤研究所分枝杆菌实验室,南京210042
  • 收稿日期:2022-03-29 修回日期:2022-08-28 发布日期:2022-12-05
  • 通讯作者: 王洪生 E-mail:whs33@vip.sina.com
  • 作者简介:作者希望10月份开录用证明。8.9 尚

Relationship between the pathogenesis of psoriasis and microbial flora

Xue Tianping1, Lu Zhenzhong1, Wang Hongsheng2   

  1. 1Department of Dermatology, Suzhou Wuzhong People′s Hospital, Suzhou 215128, China; 2Laboratory of Mycobacteriology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China
  • Received:2022-03-29 Revised:2022-08-28 Published:2022-12-05
  • Contact: Wang Hongsheng E-mail:whs33@vip.sina.com

摘要: 【摘要】 已有多项研究表明,咽部、肠道微生物及其代谢产物通过激活T淋巴细胞、树突细胞及角质形成细胞参与银屑病的发生发展与免疫调节。本文综述目前咽部、肠道微生物与银屑病发病机制相关性的研究进展。

关键词: 银屑病, 鼻咽, 胃肠道, 微生物群落, 免疫

Abstract: 【Abstract】 Several studies have indicated that pharyngeal and intestinal microflora, as well as their metabolic products, are involved in the occurrence and development of as well as immunoregulation in psoriasis by activating T lymphocytes, dendritic cells and keratinocytes. This review summarizes current research progress in the correlation of pharyngeal and intestinal microbes with the pathogenesis of psoriasis.

Key words: Psoriasis, Nasopharynx, Gastrointestinal tract, Microbial consortia, Immunity

引用本文

薛天萍 陆振中 王洪生. 【开放获取】银屑病发病机制与微生物菌群相关性研究进展[J]. 中华皮肤科杂志, 2022,e20220208. doi:10.35541/cjd.20220208

Xue Tianping, Lu Zhenzhong, Wang Hongsheng. Relationship between the pathogenesis of psoriasis and microbial flora[J]. Chinese Journal of Dermatology,2022,e20220208. doi:10.35541/cjd.20220208