中华皮肤科杂志 ›› 2023, e20210949.doi: 10.35541/cjd.20210949

• 综述 • 上一篇    下一篇

紫外线与雄激素性脱发

沈雨晴   宋秀祖   

  1. 浙江中医药大学附属杭州第三医院  杭州市第三人民医院皮肤科,杭州  310009
  • 收稿日期:2021-12-30 修回日期:2022-05-11 发布日期:2023-03-20
  • 通讯作者: 宋秀祖 E-mail:songxiuzu@sina.com
  • 基金资助:
    国家自然科学基金(81872517)

Ultraviolet and androgenetic alopecia

Shen Yuqing, Song Xiuzu   

  1. Department of Dermatology, Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou Third People′s Hospital, Hangzhou 310009, China
  • Received:2021-12-30 Revised:2022-05-11 Published:2023-03-20
  • Contact: Song Xiuzu E-mail:songxiuzu@sina.com
  • Supported by:
    National Natural Science Foundation of China(81872517)

摘要: 紫外线照射可能促进雄激素性脱发(AGA)的发生。紫外线照射一方面通过氧化应激和微生态变化引起毛囊周围炎症,同时吸引角质形成细胞、黑素细胞及肥大细胞参与毛囊微炎症;另一方面可以引起毛囊干细胞、毛乳头细胞以及真皮成纤维细胞老化和弹力纤维增加,促进AGA。本文综述近年相关文献,为倡导头发与头皮防晒从而预防AGA提供参考。

关键词: 紫外线, 秃发, 炎症, 细胞衰老, 雄激素性脱发

Abstract: Ultraviolet exposure may promote the development of androgenetic alopecia. On the one hand, ultraviolet irradiation can cause perifollicular inflammation through oxidative stress and microecological changes, and can also induce keratinocytes, melanocytes and mast cells to participate in the development of follicular microinflammation; on the other hand, ultraviolet irradiation can cause the aging of hair follicle stem cells, dermal papilla cells and dermal fibroblasts, as well as the increase of elastic fibers. This review summarizes relevant literature in recent years, in order to provide a theoretical basis for advocating protection of the hair and scalp against sunlight to prevent androgenetic alopecia.

Key words: Ultraviolet rays, Alopecia, Inflammation, Cell aging, Androgenetic alopecia

引用本文

沈雨晴 宋秀祖. 紫外线与雄激素性脱发[J]. 中华皮肤科杂志, 2023,e20210949. doi:10.35541/cjd.20210949

Shen Yuqing, Song Xiuzu. Ultraviolet and androgenetic alopecia[J]. Chinese Journal of Dermatology,2023,e20210949. doi:10.35541/cjd.20210949