中华皮肤科杂志 ›› 2021, Vol. 54 ›› Issue (2): 178-182.doi: 10.35541/cjd.20190864
叶瑞贤 薛如君 梁景耀 刘焕颜 熊绮颖 董良娇 张锡宝
收稿日期:
2019-08-29
修回日期:
2020-02-05
发布日期:
2021-01-29
通讯作者:
张锡宝
E-mail:zxibao@126.com
基金资助:
Ye Ruixian, Xue Rujun, Liang Jingyao, Liu Huanyan, Xiong Qiying, Dong Liangjiao, Zhang Xibao
Received:
2019-08-29
Revised:
2020-02-05
Published:
2021-01-29
Contact:
Zhang Xibao
E-mail:zxibao@126.com
Supported by:
摘要: 【摘要】 microRNA(miRNA)是一类转录后调控基因表达的非编码RNA分子,参与皮肤各种病理生理过程。近年来,miRNA表达谱的变化已被报道与部分炎症性皮肤病相关,例如miR-203、miR-146a、miR-21在银屑病皮损中表达上调;miR-155、miR-146a在特应性皮炎皮损中表达上调;miR-21、miR-223、miR-142-3p、miR142-5p在过敏性接触性皮炎皮损表达上调;而miR-146a、miR-155在系统性红斑狼疮患者外周血表达下调;miR-223在皮肌炎皮损中表达下调等。本文综述miRNA与部分炎症性皮肤病发生、发展之间的联系。
叶瑞贤 薛如君 梁景耀 刘焕颜 熊绮颖 董良娇 张锡宝. microRNA在炎症性皮肤病中作用的研究进展[J]. 中华皮肤科杂志, 2021,54(2):178-182. doi:10.35541/cjd.20190864
Ye Ruixian, Xue Rujun, Liang Jingyao, Liu Huanyan, Xiong Qiying, Dong Liangjiao, Zhang Xibao. Role of microRNAs in inflammatory skin diseases[J]. Chinese Journal of Dermatology, 2021, 54(2): 178-182.doi:10.35541/cjd.20190864
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