特应性皮炎的临床表型和内表型

doi:10.35541/cjd.20190741

中华皮肤科杂志 ›› 2021, Vol. 54 ›› Issue (3): 259-263.doi: 10.35541/cjd.20190741

特应性皮炎的临床表型和内表型

周杰宋志强

陆军军医大学附属西南医院皮肤科，重庆 400038

收稿日期:2019-07-12 修回日期:2020-09-28 发布日期:2021-03-02
通讯作者: 宋志强 E-mail:drsongzq@hotmail.com
基金资助:
国家自然科学基金（81673059）

Clinical phenotypes and endophenotypes of atopic dermatitis

Zhou Jie, Song Zhiqiang

Department of Dermatology, The Southwest Hospital of Army Medical University, Chongqing 400038, China

Received:2019-07-12 Revised:2020-09-28 Published:2021-03-02
Contact: Song Zhiqiang E-mail:drsongzq@hotmail.com
Supported by:
National Natural Science Foundation of China（81673059）

摘要/Abstract

摘要： 【摘要】特应性皮炎患者的临床表型及内表型多样，明确不同临床表型及内表型的特征，对协助诊断并实施针对性治疗有重要意义。本文从特应性皮炎不同发病年龄、种族背景及疾病严重程度等方面综述其临床表型差异，概述内表型及相关生物标志物的临床意义。

关键词: 皮炎, 特应性, 皮肤表现, 临床表型, 内表型, 生物标志物

Abstract: 【Abstract】 Clinical phenotypes and endophenotypes of atopic dermatitis are diverse, and it is of great significance to identify characteristics of different clinical phenotypes and endophenotypes for auxiliary diagnosis and targeted treatments. This review elaborates differences in clinical phenotypes of atopic dermatitis in terms of age of onset, ethnic background, disease severity, etc., and summarizes clinical significance of endophenotypes and related biomarkers.

Key words: Dermatitis, atopic, Skin manifestations, Clinical phenotype, Endophenotype, Biomarker

周杰宋志强. 特应性皮炎的临床表型和内表型[J]. 中华皮肤科杂志, 2021,54(3):259-263. doi:10.35541/cjd.20190741

Zhou Jie, Song Zhiqiang. Clinical phenotypes and endophenotypes of atopic dermatitis[J]. Chinese Journal of Dermatology, 2021, 54(3): 259-263.doi:10.35541/cjd.20190741

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特应性皮炎的临床表型和内表型

Clinical phenotypes and endophenotypes of atopic dermatitis

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