中华皮肤科杂志 ›› 2021, Vol. 54 ›› Issue (7): 639-641.doi: 10.35541/cjd.20210124

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脂溢性皮炎样皮肌炎：一种特殊类型的皮肌炎

杨骥    徐欣植    李明   

  1. 复旦大学附属中山医院皮肤科，上海  200032
  • 收稿日期:2021-02-04 修回日期:2021-04-20 发布日期:2021-07-02
  • 通讯作者: 杨骥 E-mail:yang.ji@zs-hospital.sh.cn
  • 基金资助:
    国家自然科学基金（82073436）；上海市科技计划项目（20ZR1411500、19411962500）；上海市“医苑新星”青年医学人才培养资助计划；复旦大学“卓越2025”人才培育计划

Seborrheic dermatitis-distributed dermatomyositis: a special type of dermatomyositis

Yang Ji, Xu Xinzhi, Li Ming   

  1. Department of Dermatology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
  • Received:2021-02-04 Revised:2021-04-20 Published:2021-07-02
  • Contact: Yang Ji E-mail:yang.ji@zs-hospital.sh.cn
  • Supported by:
    National Natural Science Foundation of China （82073436）; Medical Guide Project from Science and Technology Commission of Shanghai Municipality （CN） （20ZR1411500, 19411962500）; Outstanding Youth Medical Talents of Shanghai "Rising Stars of Medical Talent" Youth Development Program; Zhuoxue Plan of Fudan University

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摘要： 【摘要】 介绍一种特殊类型的皮肌炎——脂溢性皮炎样皮肌炎，其特点为患者有面部脂溢性皮炎样皮疹，常伴有Gottron丘疹、反向Gottron丘疹、技工手和皮肤溃疡，很少累及肌肉。抗黑素瘤分化相关基因5抗体阳性的脂溢性皮炎样皮肌炎患者更易出现肺间质病变/急进性肺间质病变。通过皮疹联合抗体检测可对脂溢性皮炎样皮肌炎进行早期诊断，早期积极联合糖皮质激素和免疫抑制剂治疗可以提高患者的生存率。

关键词: 皮肌炎, 脂溢性皮炎样皮肌炎, 肺间质病变

Abstract: 【Abstract】 Seborrheic dermatitis-distributed dermatomyositis, a special type of dermatomyositis, is characterized by facial seborrheic dermatitis-distributed rashes, usually accompanied by Gottron papules, inverse Gottron papules, mechanic′s hands and skin ulcers, seldom accompanied by muscle involvement. Anti-melanoma differentiation-associated gene 5 （MDA5） antibody-positive patients with seborrheic dermatitis-distributed dermatomyositis are prone to interstitial lung disease/rapidly progressive interstitial lung disease. Early diagnosis of seborrheic dermatitis-distributed dermatomyositis can be made through the combination of rashes and antibody detection, and early and active combined treatment with glucocorticoids and immunosuppressors can improve the survival rate of patients.

Key words: Dermatomyositis, Seborrheic dermatitis-distributed dermatomyositis, Interstitial lung disease

引用本文

杨骥 徐欣植 李明. 脂溢性皮炎样皮肌炎：一种特殊类型的皮肌炎[J]. 中华皮肤科杂志, 2021,54(7):639-641. doi:10.35541/cjd.20210124

Yang Ji, Xu Xinzhi, Li Ming. Seborrheic dermatitis-distributed dermatomyositis: a special type of dermatomyositis[J]. Chinese Journal of Dermatology, 2021, 54(7): 639-641.doi:10.35541/cjd.20210124