诱发性银屑病样动物模型的研究进展

doi:10.35541/cjd.20250129

Abstract

Abstract: 【Abstract】 Animal models are crucial tools in psoriasis research, with induced psoriasis-like models being widely employed. Induction methods include topical application, injection, and oral administration, such as psoriasis like animal models induced by the topical application of imiquimod, intraperitoneal injection of mannan, and oral administration of propranolol. These models exhibit high similarity to human psoriatic lesions and offer significant advantages in reproducibility, stability, and practicality. They have become essential tools for investigating psoriasis pathogenesis, exploring therapeutic targets, and evaluating treatment efficacy. This review summarizes current research progress on induced psoriasis?like animal models and analyzes existing challenges.

Key words: Psoriasis, Models, animal, Imiquimod, Propranolol, Mannans, Cytokines

Wang Yongxing, Ding Yuan. Induced psoriasis-like animal models[J]. Chinese Journal of Dermatology,2026,e20250129. doi:10.35541/cjd.20250129

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Induced psoriasis-like animal models

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