Chinese Journal of Dermatology ›› 2023, Vol. 56 ›› Issue (12): 1091-1095.doi: 10.35541/cjd.20230347

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Photohardening therapy for idiopathic actinic dermatoses

Deng Huiyan, Chen Jiaoquan, Li Huaping, Chen Quan, Zhang Sanquan, Zhu Huilan   

  1. Department of Dermatology, Guangzhou Institute of Dermatology, Institute of Dermatology, Guangzhou Medical University, Guangzhou 510095, China
  • Received:2023-06-15 Revised:2023-09-28 Online:2023-12-15 Published:2023-12-05
  • Contact: Zhu Huilan
  • Supported by:
    Science and Technology Program of Guangzhou(2023A03J0947)

Abstract: 【Abstract】 Photohardening therapy, also known as photodesensitization therapy, refers to the phototherapy and photochemotherapy of idiopathic actinic dermatoses, and its goal is to improve the patients′ tolerance to sunlight and prevent disease flares. Its mechanisms of action involve a variety of cellular and inflammatory factors. This therapy is suitable for all idiopathic actinic dermatoses, with definite efficacy and good safety. However, the treatment specificity usually leads to poor compliance. The development of UVA1 rush hardening and home phototherapy is expected to solve this problem.

Key words: Photosensitivity disorders, Idiopathic actinic dermatoses, Photohardening therapy, Photodesensitization therapy, UVA1 rush hardening, Home phototherapy