Abstract:

Hao Yangyang, Zhang Liangyu, Chen Yang Department of Dermatology, 98th Hospital of People′s Liberation Army, 98th Clinical College of People′s Liberation Army, Anhui Medical University, Huzhou 313000, Zhejiang, China Corresponding author: Chen Yang, Email: 98cy@163.com 【Abstract】 Hyperbaric oxygen （HBO） therapy is the inhalation of 100% oxygen at a pressure higher than one atmosphere absolute （ATA）, and has been used as an auxiliary therapy for various skin diseases. It has been proved that HBO can increase the oxygen content in skin tissues, accelerate aerobic metabolism of skin, promote epithelial regeneration and wound healing, relieve adverse stimuli on peripheral nerves and sensors in the skin, inhibit apoptosis of neurons, enhance the function of regulatory T cells, alleviate inflammation, and mobilize vascular stem/progenitor cells （SPCs） from the bone marrow to peripheral blood and ulcer tissues. At present, HBO has been widely applied in the auxiliary treatment of psoriasis, atopic dermatitis, postherpetic neuralgia, chronic refractory cutaneous ulcer, pyoderma gangrenosum, fungal infection, vascular embolization after cosmetic facial filling, and some other skin diseases.