Abstract: Liu Wei, Hu Bai, Zhao Zhenglong, Zhang Siping, Jiang Faxing, Liu Qiong. Department of Dermatology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China Corresponding author：Hu Bai, Email: hu_bai@126.com 【Abstract】 Objective To analyze the clinical feature and prognostic predictors of disseminated herpes zoster. Methods A retrospective study was carried out on 76 patients with disseminated herpes zoster collected from 2005 to 2012 in the Department of Dermatology, Anhui Provincial Hospital. Statistical analysis and comparisons were done. Results The incidence rate of disseminated herpes zoster was highest in the three age groups: 70 － 79 years, 30 － 39 years, and 60 － 69 years. Of these patients, 59.21% suffered from complications, and 44.74% from postherpetic neuralgia. Logistic regression analysis showed that the occurrence of complications was significantly associated with age and impaired cellular immune function, and the incidence of postherpetic neuralgia with age, impaired cellular immune function and presence of underlying diseases. Conclusions There is a high incidence of complications in patients with disseminated herpes zoster, and impaired cellular immune function may be an important factor affecting its prognosis.

Key words: Herpes zoster, Regression analysis, Risk factors