白癜风角朊细胞内皮素1mRNA表达的研究

Abstract

Abstract: Objective To study the expression of endothelin-1 (ET-1) mRNA in keratinocytes in patients with vitiligo. Methods Fourteen patients with progressive vitiligo were measured by hybridization in situ. Results Our results showed that the expression of ET-1 mRNA was markedly decreased. Conclusion The results revealed that decreased ET-1 expression may be associated with the pathogenesis of vitiligo. The cause and role of decreasing of ET-1 expression of keratinocyte in vitiligo lesion need to be studied further.

Key words: Vitiligo, Keratinocytes, Endothelins

Chang Jianmin, Zhu Tiejun, Ma Shengqing. Study on the Expression of Endothelin 1 mRNA in Keratinocytes in Patients with Vitiligo[J].Chinese Journal of Dermatology, 1998, 31(4): 215-217.

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Study on the Expression of Endothelin 1 mRNA in Keratinocytes in Patients with Vitiligo

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