Chinese Journal of Dermatology ›› 2019, Vol. 52 ›› Issue (4): 279-282.doi: 10.3760/cma.j.issn.0412-4030.2019.04.013

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Application of platelet-rich plasma in dermatology

Hou Xiaoyuan, Lu Yan   

  1. Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
  • Received:2018-04-03 Revised:2018-08-06 Online:2019-04-15 Published:2019-04-01
  • Contact: Lu Yan

Abstract: 【Abstract】 Platelet-rich plasma (PRP) is a platelet concentrate isolated from the autologous whole blood after centrifugation, and its optimal working concentration is 4 - 7 times that of the blood platelet count in the whole blood. After the activation by thrombin or calcium chloride, platelets can release various growth factors, which can promote hemostasis, wound healing and angiogenesis. Considered as a kind of low-cost and safe therapy, it has been widely applied to the repair of soft tissue and hard tissue injuries. PRP has also been widely applied to dermatology, including hair loss, skin rejuvenation, scar repair and wound healing. This review summarizes the application of PRP in dermatology.

Key words: Platelet-rich plasma, Alopecia, Vitiligo, Striae distensae, Cicatrix, Wound healing, Rejuvenation