Abstract: Three rare cases of angiotropic lymphoma were reported with a review of literature.The early clinical manifestations were skin nodules and/or purpura associated with fever and the elevation of LDH and AKP.Histopathological examination show ed that multifocal proliferation of neoplastic mononuclear cells infiltrated into the lumina of small blood vessels and resulted in the destruction of the vascular walls and surrounding structures.Immunohistochemical study confirmed its T-celorigin.The prognosis of the diseaseis poor but the patient's survival time can be prolonged with early diagnosis and proper treatment.This is the first report of such disease in our country.

Key words: Lymphoma, angiotropic, Tlymphocytes