Chinese Journal of Dermatology ›› 1993, Vol. 26 ›› Issue (5): 291-293.

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Expression of Leu-7 and Leu-llb Antigens on Keratinocytes in Some Derrnatoses

HE Chun-Di1   

  1. Department of Dermatology, No.1 Hospital, China Medical Unirersity, Shengyang 110001
  • Received:1992-08-07 Revised:1995-01-03 Online:1993-10-15 Published:1993-10-15

Abstract: Employing an avidin-biotin complex immunoperoxidase techrxique,we observed an obvious expression of Leu-7 and Leu-11b anti gens on the keratinocytes of upper epidermis in lesions of squamoug cell carcinoma,basal cell carcinoma,sebarrheic keratosis,urticaria pigmentosa,nevus pigmentasus,lichen planar,psoriasis wlgaris and parapsoriasis.It could be assumed that the keratinoeytes in lesions of some dermatoses might possess the function of non-MHC-restricted cytotoxccfty.

Key words: Antibodies, monoclonal Keratinocytes