Abstract: This paper reports the effect on palmoplantar sweatang of rnice with tapsvater MUIIC iontophoresis. The results showed: 1. The quanity of sweat and the number of active sweat glands decreased after treatment and there was marked difference the tapwater MUIIC inotnphoresis and tapwater immersion, 0.5% scopolamine solution immersion, 5% formalin solution inurtction in automatch control (P<0.01 and 0.05 respectively).