Chinese Journal of Dermatology ›› 2022, Vol. 55 ›› Issue (8): 735-739.doi: 10.35541/cjd.20220001

• Reviews • Previous Articles     Next Articles

Treatment of some genodermatoses

Jin Liang1, Liu Ling2   

  1. 1Department of Dermatology, Air Force Medical Center, PLA, Beijing 100142, China; 2Department of Dermatology, Xijing Hospital, The Fourth Military Medical University, Xi′an 710032, China
  • Received:2022-01-04 Revised:2022-02-25 Online:2022-08-15 Published:2022-08-02
  • Contact: Liu Ling E-mail:vanilla@fmmu.edu.cn
  • Supported by:
    "Young Eagle Program of Talent Project" of Air Force Military Medical University(KT2021HQ021)

Abstract: 【Abstract】 Genodermatoses are a relatively independent type of skin diseases, with early onset, complex clinical manifestations and multiple system involvement. Current treatments of genodermatoses are still limited with poor therapeutic effect, and the quality of life of patients is greatly affected. This review summarizes prospective treatment methods of some hereditary skin diseases and related research progress, including innovative application of traditional medicines, biologics and small-molecule targeted drugs, stem cell therapy and gene editing, aiming to provide more reference for clinicians.

Key words: Skin diseases, genetic, Therapy, Biological agents, Stem cells, Small molecular targeted drugs, Gene editing