Chinese Journal of Dermatology ›› 2021, Vol. 54 ›› Issue (1): 1-9.doi: 10.35541/cjd.20200731
• Guidelines and Consensus • Previous Articles Next Articles
Photodynamic Therapy Research Center, Chinese Society of Dermatology; Chinese Association of Rehabilitation Dermatology; Photomedicine Therapeutic Equipment Group, Committee on Skin Disease and Cosmetic Dermatology, China Association of Medical Equipment
Received:
2020-07-21
Revised:
2020-11-20
Online:
2021-01-15
Published:
2021-01-05
Contact:
Wang Xiuli; Gu Heng
E-mail:wangxiuli20150315@163.com; guheng@aliyun.com
Photodynamic Therapy Research Center, Chinese Society of Dermatology, Chinese Association of Rehabilitation Dermatology, Photomedicine Therapeutic Equipment Group, Committee on Skin Disease and Cosmetic Dermatology, China Association of Medical Equipment. Chinese guidelines for clinical application of aminolevulinic acid-based photodynamic therapy in dermatology (2021 edition)[J]. Chinese Journal of Dermatology, 2021, 54(1): 1-9.doi:10.35541/cjd.20200731
Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks
[1] | Kennedy JC, Pottier RH, Pross DC. Photodynamic therapy with endogenous protoporphyrin Ⅸ: basic principles and present clinical experience[J]. J Photochem Photobiol B, 1990,6(1⁃2):143⁃148. doi: 10.1016/1011⁃1344(90)85083⁃9. |
[2] | Wang XL, Wang HW, Wang HS, et al. Topical 5⁃aminolaevulinic acid⁃photodynamic therapy for the treatment of urethral condylomata acuminata[J]. Br J Dermatol, 2004,151(4):880⁃885. doi: 10.1111/j.1365⁃2133.2004.06189.x. |
[3] | 涂平, 郑和义, 顾恒, 等. 外用盐酸氨基酮戊酸光动力疗法治疗尖锐湿疣多中心随机对照研究[J]. 中华皮肤科杂志, 2007,40(2):67⁃70. doi: 10.3760/j.issn:0412⁃4030.2007.02.001. |
[4] | Morton CA, Szeimies RM, Basset⁃Seguin N, et al. European Dermatology Forum guidelines on topical photodynamic therapy 2019 part 1: treatment delivery and established indications ⁃ actinic keratoses, Bowen′s disease and basal cell carcinomas[J]. J Eur Acad Dermatol Venereol, 2019,33(12):2225⁃2238. doi: 10.1111/jdv.16017. |
[5] | 中华医学会皮肤性病学分会光动力治疗研究中心. 氨基酮戊酸光动力疗法临床应用专家共识[J]. 中华皮肤科杂志, 2015,48(10):675⁃678. doi: 10.3760/cma.j.issn.0412⁃4030.2015.10. 001. |
[6] | 王秀丽, 王宏伟. 光动力皮肤科实战口袋书[M]. 北京: 人民卫生出版社, 2016:20⁃21. |
[7] | Xie J, Wang S, Li Z, et al. 5⁃Aminolevulinic acid photodynamic therapy reduces HPV viral load via autophagy and apoptosis by modulating Ras/Raf/MEK/ERK and PI3K/AKT pathways in HeLa cells[J]. J Photochem Photobiol B, 2019,194:46⁃55. doi: 10.1016/j.jphotobiol.2019.03.012. |
[8] | Ji J, Wang P, Zhou Q, et al. CCL8 enhances sensitivity of cutaneous squamous cell carcinoma to photodynamic therapy by recruiting M1 macrophages[J]. Photodiagnosis Photodyn Ther, 2019,26:235⁃243. doi: 10.1016/j.pdpdt.2019.03.014. |
[9] | Ding HL, Wang XL, Wang HW, et al. Successful treatment of refractory facial acne using repeat short⁃cycle ALA⁃PDT: case study[J]. Photodiagnosis Photodyn Ther, 2011,8(4):343⁃346. doi: 10.1016/j.pdpdt.2011.07.003. |
[10] | 王佩茹, 张玲琳, 周忠霞, 等. 梅花针叩刺增强氨基酮戊酸光动力治疗光线性角化病、基底细胞癌、鳞状细胞癌的研究[J]. 中华皮肤科杂志, 2015,48(2):80⁃84. doi: 10.3760/cma.j.issn.0412⁃4030.2015.02.003. |
[11] | Bay C, Lerche CM, Ferrick B, et al. Comparison of physical pretreatment regimens to enhance protoporphyrin Ⅸ uptake in photodynamic therapy: a randomized clinical trial[J]. JAMA Dermatol, 2017,153(4):270⁃278. doi: 10.1001/jamadermatol. 2016.5268. |
[12] | 黄丹, 鞠梅, 钱伊弘, 等. 20%氨基酮戊酸光动力治疗外阴尖锐湿疣量效关系临床研究[J]. 中华皮肤科杂志, 2014,47(7):503⁃505. doi: 10.3760/cma.j.issn.0412⁃4030.2014.07.015. |
[13] | Zhu L, Wang P, Zhang G, et al. Conventional versus daylight photodynamic therapy for actinic keratosis: a randomized and prospective study in China[J]. Photodiagnosis Photodyn Ther, 2018,24:366⁃371. doi: 10.1016/j.pdpdt.2018.10.010. |
[14] | Heerfordt IM, Wulf HC. Daylight photodynamic therapy of actinic keratosis without curettage is as effective as with curettage: a randomized clinical trial[J]. J Eur Acad Dermatol Venereol, 2019,33(11):2058⁃2061. doi: 10.1111/jdv.15744. |
[15] | Ying Z, Li X, Dang H. 5⁃Aminolevulinic acid⁃based photodynamic therapy for the treatment of condylomata acuminata in Chinese patients: a meta⁃analysis[J]. Photodermatol Photoimmunol Photomed, 2013,29(3):149⁃159. doi: 10.1111/phpp.12043. |
[16] | Wang XL, Wang HW, Huang Z, et al. Study of protoporphyrin Ⅸ (PpⅨ) pharmacokinetics after topical application of 5⁃aminolevulinic acid in urethral condylomata acuminata[J]. Photochem Photobiol, 2007,83(5):1069⁃1073. doi: 10.1111/j. 1751⁃1097.2007.00178.x. |
[17] | Wang HW, Wang XL, Zhang LL, et al. Aminolevulinic acid (ALA)⁃assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region[J]. Photodiagnosis Photodyn Ther, 2008,5(4):251⁃255. doi: 10.1016/ j.pdpdt.2008.11.004. |
[18] | Chen K, Chang BZ, Ju M, et al. Comparative study of photodynamic therapy vs. CO2 laser vaporization in treatment of condylomata acuminata: a randomized clinical trial[J]. Br J Dermatol, 2007,156(3):516⁃520. doi: 10.1111/j.1365⁃2133.2006. 07648.x. |
[19] | 顾恒, 陈磊, 鞠梅, 等. 5⁃氨基酮戊酸光动力疗法联合CO2激光降低尖锐湿疣复发的临床观察[J]. 中华皮肤科杂志, 2009,42(11):802⁃803. doi: 10.3760/cma.j.issn.0412⁃4030.2009.11.039. |
[20] | Sotiriou E, Apalla Z, Vrani F, et al. Photodynamic therapy vs. imiquimod 5% cream as skin cancer preventive strategies in patients with field changes: a randomized intraindividual comparison study[J]. J Eur Acad Dermatol Venereol, 2015,29(2):325⁃329. doi: 10.1111/jdv.12538. |
[21] | Sotiriou E, Evangelou G, Papadavid E, et al. Conventional vs. daylight photodynamic therapy for patients with actinic keratosis on face and scalp: 12⁃month follow⁃up results of a randomized, intra⁃individual comparative analysis[J]. J Eur Acad Dermatol Venereol, 2018,32(4):595⁃600. doi: 10.1111/jdv.14613. |
[22] | Patel G, Armstrong AW, Eisen DB. Efficacy of photodynamic therapy vs other interventions in randomized clinical trials for the treatment of actinic keratoses: a systematic review and meta⁃analysis[J]. JAMA Dermatol, 2014,150(12):1281⁃1288. doi: 10. 1001/jamadermatol.2014.1253. |
[23] | 王宏伟, 王秀丽, 过明霞, 等. 5⁃氨基酮戊酸乳膏光动力疗法治疗皮肤癌前病变和皮肤原位癌[J]. 中华皮肤科杂志, 2006,39(3):137⁃139. doi: 10.3760/j.issn:0412⁃4030.2006.03.006. |
[24] | Wiegell SR, Fabricius S, Gniadecka M, et al. Daylight⁃mediated photodynamic therapy of moderate to thick actinic keratoses of the face and scalp: a randomized multicentre study[J]. Br J Dermatol, 2012,166(6):1327⁃1332. doi: 10.1111/j.1365⁃2133. 2012.10833.x. |
[25] | Rkein AM, Ozog DM. Photodynamic therapy[J]. Dermatol Clin, 2014,32(3):415⁃425. doi: 10.1016/j.det.2014.03.009. |
[26] | Rodríguez⁃Blanco I, Flórez Á, Paredes⁃Suárez C, et al. Actinic cheilitis prevalence and risk factors: a cross⁃sectional, multicentre study in a population aged 45 years and over in north⁃west Spain[J]. Acta Derm Venereol, 2018,98(10):970⁃974. doi: 10.2340/00015555⁃3014. |
[27] | Choi SH, Kim KH, Song KH. Efficacy of ablative fractional laser⁃assisted photodynamic therapy for the treatment of actinic cheilitis: 12⁃month follow⁃up results of a prospective, randomized, comparative trial[J]. Br J Dermatol, 2015,173(1):184⁃191. doi: 10.1111/bjd.13542. |
[28] | Radakovic S, Dangl M, Tanew A. 5⁃Aminolevulinic acid patch (Alacare) photodynamic therapy for actinic cheilitis: data from a prospective 12⁃month follow⁃up study on 21 patients[J]. J Eur Acad Dermatol Venereol, 2020,34(9):2011⁃2015. doi: 10.1111/jdv.16247. |
[29] | Szeimies RM, Ibbotson S, Murrell DF, et al. A clinical study comparing methyl aminolevulinate photodynamic therapy and surgery in small superficial basal cell carcinoma (8⁃20 mm), with a 12⁃month follow⁃up[J]. J Eur Acad Dermatol Venereol, 2008,22(11):1302⁃1311. doi: 10.1111/j.1468⁃3083.2008.02803.x. |
[30] | Peris K, Fargnoli MC, Garbe C, et al. Diagnosis and treatment of basal cell carcinoma: European consensus⁃based interdisciplinary guidelines[J]. Eur J Cancer, 2019,118:10⁃34. doi: 10.1016/j.ejca.2019.06.003. |
[31] | Morton C, Horn M, Leman J, et al. Comparison of topical methyl aminolevulinate photodynamic therapy with cryotherapy or fluorouracil for treatment of squamous cell carcinoma in situ: results of a multicenter randomized trial[J]. Arch Dermatol, 2006,142(6):729⁃735. doi: 10.1001/archderm.142.6.729. |
[32] | Aguilar⁃Bernier M, Rodríguez⁃Barón D, Rivas⁃Ruiz F, et al. Long⁃term efficacy of photodynamic therapy with methyl aminolevulinate in treating Bowen′s disease in clinical practice: a retrospective cohort study (2006 -2017)[J]. Photodermatol Photoimmunol Photomed, 2019,35(4):208⁃213. doi: 10.1111/phpp.12453. |
[33] | Fargnoli MC, Kostaki D, Piccioni A, et al. Photodynamic therapy for the treatment of microinvasive squamous cell carcinoma of the lower lip: a case report[J]. G Ital Dermatol Venereol, 2015,150(3):331⁃335. |
[34] | Calzavara⁃Pinton PG, Venturini M, Sala R, et al. Methylaminolaevulinate⁃based photodynamic therapy of Bowen′s disease and squamous cell carcinoma[J]. Br J Dermatol, 2008,159(1):137⁃144. doi: 10.1111/j.1365⁃2133.2008.08593.x. |
[35] | Bu W, Wang Y, Chen X, et al. Novel strategy in giant cutaneous squamous cell carcinoma treatment: the case experience with a combination of photodynamic therapy and surgery[J]. Photodiagnosis Photodyn Ther, 2017,19:116⁃118. doi: 10.1016/j.pdpdt.2017.05.006. |
[36] | Wang P, Zhang L, Zhang G, et al. Successful treatment of giant invasive cutaneous squamous cell carcinoma by plum⁃blossom needle assisted photodynamic therapy sequential with imiquimod: case experience[J]. Photodiagnosis Photodyn Ther, 2018,21:393⁃395. doi: 10.1016/j.pdpdt.2017.12.010. |
[37] | Nicklas C, Rubio R, Cárdenas C, et al. Comparison of efficacy of aminolaevulinic acid photodynamic therapy vs. adapalene gel plus oral doxycycline for treatment of moderate acne vulgaris⁃⁃a simple, blind, randomized, and controlled trial[J]. Photodermatol Photoimmunol Photomed, 2019,35(1):3⁃10. doi: 10.1111/phpp.12413. |
[38] | Keyal U, Bhatta AK, Wang XL. Photodynamic therapy for the treatment of different severity of acne: a systematic review[J]. Photodiagnosis Photodyn Ther, 2016,14:191⁃199. doi: 10.1016/j.pdpdt.2016.04.005. |
[39] | Ma L, Xiang LH, Yu B, et al. Low⁃dose topical 5⁃aminolevulinic acid photodynamic therapy in the treatment of different severity of acne vulgaris[J]. Photodiagnosis Photodyn Ther, 2013,10(4):583⁃590. doi: 10.1016/j.pdpdt.2013.06.007. |
[40] | 张玲琳, 王秀丽, 王宏伟, 等. 5⁃氨基酮戊酸光动力疗法治疗痤疮[J]. 中华皮肤科杂志, 2009,42(2):78⁃80. doi: 10.3760/cma.j.issn.0412⁃4030.2009.02.003. |
[41] | Wang HW, Lv T, Zhang LL, et al. Prospective study of topical 5⁃aminolevulinic acid photodynamic therapy for the treatment of moderate to severe acne vulgaris in Chinese patients[J]. J Cutan Med Surg, 2012,16(5):324⁃333. doi: 10.1177/12034754120160 0509. |
[42] | 吕婷, 王秀丽, 王宏伟. 5⁃氨基酮戊酸光动力疗法治疗光老化[J]. 国际皮肤性病学杂志, 2009,35(4):214⁃216. doi: 10.3760/cma.j.issn.1673⁃4173.2009.04.009. |
[43] | Ji J, Zhang LL, Ding HL, et al. Comparison of 5⁃aminolevulinic acid photodynamic therapy and red light for treatment of photoaging[J]. Photodiagnosis Photodyn Ther, 2014,11(2):118⁃121. doi: 10.1016/j.pdpdt.2014.02.007. |
[44] | Clementoni MT, B⁃Roscher M, Munavalli GS. Photodynamic photorejuvenation of the face with a combination of microneedling, red light, and broadband pulsed light[J]. Lasers Surg Med, 2010,42(2):150⁃159. doi: 10.1002/lsm.20905. |
[45] | Sanclemente G, Medina L, Villa JF, et al. A prospective split⁃face double⁃blind randomized placebo⁃controlled trial to assess the efficacy of methyl aminolevulinate + red⁃light in patients with facial photodamage[J]. J Eur Acad Dermatol Venereol, 2011,25(1):49⁃58. doi: 10.1111/j.1468⁃3083.2010.03687.x. |
[46] | 中国医师协会皮肤科医师分会皮肤激光与理疗亚专业委员会. 强脉冲光临床应用专家共识(2017)[J]. 中华皮肤科杂志, 2017,50(10):701⁃705. doi: 10.3760/cma.j.issn.0412⁃4030. 2017.10.001. |
[47] | Xi Z, Shuxian Y, Zhong L, et al. Topical 5⁃aminolevulinic acid with intense pulsed light versus intense pulsed light for photodamage in Chinese patients[J]. Dermatol Surg, 2011,37(1):31⁃40. doi: 10.1111/j.1524⁃4725.2010.01726.x. |
[48] | Zhang HY, Ji J, Tan YM, et al. Evaluation of 5⁃aminolevulinic acid⁃mediated photorejuvenation of neck skin[J]. Photodiagnosis Photodyn Ther, 2014,11(4):498⁃509. doi: 10.1016/j.pdpdt.2014. 10.003. |
[49] | Shi M, He S, Chen P, et al. Photodynamic therapy in a patient with facial angiofibromas due to tuberous sclerosis complex[J]. Photodiagnosis Photodyn Ther, 2019,28:183⁃185. doi: 10.1016/j.pdpdt.2019.08.009. |
[50] | Zheng X, He S, Li Q, et al. Successful treatment of verrucous epidermal nevus with fractional micro⁃plasma radio⁃frequency technology and photodynamic therapy[J]. J Cosmet Laser Ther, 2018,20(6):357⁃359. doi: 10.1080/14764172.2018.1511914. |
[51] | Morton CA, Szeimies RM, Basset⁃Séguin N, et al. European Dermatology Forum guidelines on topical photodynamic therapy 2019 part 2: emerging indications ⁃ field cancerization, photorejuvenation and inflammatory/infective dermatoses[J]. J Eur Acad Dermatol Venereol, 2020,34(1):17⁃29. doi: 10.1111/jdv.16044. |
[52] | Shi L, Miao F, Zhang LL, et al. Comparison of 5⁃aminolevulinic acid photodynamic therapy and clobetasol propionate in treatment of vulvar lichen sclerosus[J]. Acta Derm Venereol,2016,96(5):684⁃688. doi: 10.2340/00015555⁃2341. |
[53] | Wang B, Shi L, Zhang YF, et al. Gain with no pain? Pain management in dermatological photodynamic therapy[J]. Br J Dermatol, 2017,177(3):656⁃665. doi: 10.1111/bjd.15344. |
[54] | Zheng Z, Zhang LL, Shi L, et al. What is the most relevent factor causing pain during ALA⁃PDT? A multi⁃center, open clinical pain score research trial of actinic keratosis, acne and condylomata acuminata[J]. Photodiagnosis Photodyn Ther, 2019,26:73⁃78. doi: 10.1016/j.pdpdt.2019.03.001. |
[55] | Ibbotson SH, Wong TH, Morton CA, et al. Adverse effects of topical photodynamic therapy: a consensus review and approach to management[J]. Br J Dermatol, 2019,180(4):715⁃729. doi: 10.1111/bjd.17131. |
[56] | Angell⁃Petersen E, Christensen C, Müller CR, et al. Phototoxic reaction and porphyrin fluorescence in skin after topical application of methyl aminolaevulinate[J]. Br J Dermatol, 2007,156(2):301⁃307. doi: 10.1111/j.1365⁃2133.2006.07638.x. |
[57] | López V, López I, Ramos V, et al. Erosive pustular dermatosis of the scalp after photodynamic therapy[J/OL]. Dermatol Online J, 2012,18(9):13[2020⁃04⁃26]. https://escholarship.org/uc/item/33b9s5wb. |
[58] | Wolfe CM, Green WH, Hatfield HK, et al. Urticaria after methyl aminolevulinate photodynamic therapy in a patient with nevoid basal cell carcinoma syndrome[J]. J Drugs Dermatol, 2012,11(11):1364⁃1365. |
[59] | Zhou Q, Wang P, Zhang L, et al. Pemphigus vulgaris induced by 5⁃aminolaevulinic acid⁃based photodynamic therapy[J]. Photodiagnosis Photodyn Ther, 2017,19:156⁃158. doi: 10.1016/j.pdpdt.2017.05.014. |
[60] | Rakvit P, Kerr AC, Ibbotson SH. Localized bullous pemphigoid induced by photodynamic therapy[J]. Photodermatol Photoimmunol Photomed, 2011,27(5):251⁃253. doi: 10.1111/j. 1600⁃0781.2011.00609.x. |
[61] | Zhang Y, Zhang H, Zhang L, et al. Modified 5⁃aminolevulinic acid photodynamic therapy to reduce pain in the treatment of moderate to severe acne vulgaris: a prospective, randomized split⁃face study[J]. J Am Acad Dermatol, 2021,84(1):218⁃220. doi: 10.1016/j.jaad.2020.04.146. |
[1] | Zhang Yuanwen, Sun Congqian, Pan Wendong. Off-label clinical application of botulinum toxin in dermatology [J]. Chinese Journal of Dermatology, 2024, 57(5): 471-475. |
[2] | STAR-Dermatology Professional Committee. Scientificity, transparency and applicability rankings of Chinese dermatological guidelines and consensus published in medical journals in 2022 [J]. Chinese Journal of Dermatology, 2024, 57(2): 141-146. |
[3] | Chen Yaolong, Liu Hui, Yao Zhirong, Gao Xinghua. Strategies and suggestions for improving the quality of guidelines and consensus in the field of dermatology [J]. Chinese Journal of Dermatology, 2023, 56(9): 805-808. |
[4] | Zhong Jiemin, Shao Lei, Liang Yimin, Huang Qiongxiao, Xia Manqi, Liu Yumei. Comparative study on efficacy and safety of single microneedle radiofrequency versus photodynamic therapy in the treatment of inflammatory lesions of moderate to severe facial acne vulgaris [J]. Chinese Journal of Dermatology, 2023, 56(8): 751-755. |
[5] | Committee on Psoriasis, Chinese Society of Dermatology. Guideline for the diagnosis and treatment of psoriasis in China (2023 edition) [J]. Chinese Journal of Dermatology, 2023, 56(7): 573-625. |
[6] | Li Rong, Zhang Jiaan, Chen Kun. Photoelectric therapy for rosacea [J]. Chinese Journal of Dermatology, 2023, 56(5): 468-470. |
[7] | Jin Hui, Lu Qianjin, . Exploring the application of inquiry-based defensive teaching based on the internet and clinical resources during probationary teaching of dermatovenereology [J]. Chinese Journal of Dermatology, 2023, 56(4): 353-356. |
[8] | Liu Lihao, Hu Yu, Chen Kun. Clinical application and development of photobiomodulation in dermatology [J]. Chinese Journal of Dermatology, 2023, 0(2): 20230312-e20230312. |
[9] | Chen Kun, Gu Heng. Research progress and directions in photodermatology [J]. Chinese Journal of Dermatology, 2023, 56(12): 1087-1090. |
[10] | Zhu He, Wu Yingying, Yang Rongya, Wang Congmin, Ao Junhong. Efficacy of medical cold patches in relieving burning pain and restoring skin homeostasis after hematoporphyrin monomethyl ether-based photodynamic therapy for the treatment of port-wine stains [J]. Chinese Journal of Dermatology, 2022, 55(9): 784-789. |
[11] | Feng Hua, Gao Yingshu, Li Qing, Sun Lianwen. Cell mechanics in dermatology [J]. Chinese Journal of Dermatology, 2022, 55(7): 641-644. |
[12] | Liu Yuzhen, Zeng Rong, Zheng Nana, Duan Zhimin, Xu Haoxiang, Wu Qiuju, Lin Tong, Li Min. Effect of different incubation time of aminolevulinic acid on photodynamic inhibition of Propionibacterium acnes biofilms [J]. Chinese Journal of Dermatology, 2022, 55(3): 208-212. |
[13] | Chinese Dermatologist Association. Expert consensus on clinical application of aminolevulinic acid-based photodynamic therapy in the treatment of acne vulgaris (2022) [J]. Chinese Journal of Dermatology, 2022, 55(12): 1050-1057. |
[14] | Hu Yanyan, Jiang Qian, Chen Liuqing, Li Dongsheng. Application of reflectance confocal microscopy in the evaluation of clinical efficacy of hemoporfin-mediated photodynamic therapy for purple-type port-wine stain [J]. Chinese Journal of Dermatology, 2021, 54(4): 342-346. |
[15] | Deng Qing, Liu Fangfen, Shi Wei, Xie Hongfu, Li Ji, Huang Yingxue. Willingness to pay for treatment of rosacea and its influencing factors: a survey of patients in Changsha region [J]. Chinese Journal of Dermatology, 2021, 54(4): 352-355. |
|