Chinese Journal of Dermatology ›› 2020, Vol. 53 ›› Issue (7): 501-507.doi: 10.35541/cjd.20200603

• Expert Commentary • Previous Articles     Next Articles

Diagnosis and treatment of hemangiomas and vascular malformations: current status and prospect

Li Li,Zhang Bin ,Wei Li ,Ma Lin   

  1. Department of Dermatology, Beijing Children′s Hospital, Capital Medical University, National Center for Children′s Health, Beijing 100045, China
  • Received:2020-06-15 Revised:2020-06-18 Online:2020-07-15 Published:2020-07-06
  • Contact: Ma Lin E-mail:bch_maleen@aliyun.com

Abstract: 【Abstract】 Hemangiomas and vascular malformations are common diseases in children. With the continuous update of disease classification criteria, their diagnosis and treatment have also gradually developed. Infantile hemangioma has a good prognosis, but the timing and method of treatment are crucial to the prognosis. Beta-blockers are the first-line drugs for the treatment of infantile hemangioma. The correct diagnosis and differential diagnosis of vascular malformations, especially some vascular malformation-related syndromes with low incidence, are still challenges in the field of modern medicine. Recent studies have shown that the pathogenesis of vascular malformations is associated with mutations in related genes, which provides a theoretical basis for targeted drug therapy. Multidisciplinary integration is the future trend in the diagnosis and treatment of vascular malformations. This review describes the current status of, as well as problems and future research directions in the diagnosis and treatment of common hemangiomas and vascular malformations.

Key words: Hemangioma, Vascular malformations, Lymphatic abnormalities, Diagnosis, Therapy