Chinese Journal of Dermatology ›› 2019, Vol. 52 ›› Issue (11): 801-807.doi: 10.35541/cjd.20190241
• Original Articles • Previous Articles Next Articles
Wang Yanqin1, Li Xinxin1, Xue Haibo2, Ji Hong3, Sun Dakang4, Ma Lei1
Received:
2019-01-17
Revised:
2019-08-12
Online:
2019-11-15
Published:
2019-11-04
Contact:
Ma Lei
E-mail:doctor_malei@126.com
Supported by:
Wang Yanqin, Li Xinxin, Xue Haibo, Ji Hong, Sun Dakang, Ma Lei. Effect of Notch-Hes1 signaling blockade by a γ-secretase inhibitor on the expression of γδT17 cells in a mouse model of psoriasis-like skin inflammation[J].Chinese Journal of Dermatology, 2019, 52(11): 801-807.
[1] | Lowes MA, Suárez⁃Fariñas M, Krueger JG. Immunology of psoriasis[J]. Annu Rev Immunol, 2014,32:227⁃255. doi: 10.1146/ annurev⁃immunol⁃032713⁃120225. |
[2] | Adami S, Cavani A, Rossi F, et al. The role of interleukin⁃17A in psoriatic disease[J]. BioDrugs, 2014,28(6):487⁃497. doi: 10. 1007/s40259⁃014⁃0098⁃x. |
[3] | Malakouti M, Brown GE, Wang E, et al. The role of IL⁃17 in psoriasis[J]. J Dermatolog Treat, 2015,26(1):41⁃44. |
[4] | Silfvast⁃Kaiser A, Paek SY, Menter A. Anti⁃IL17 therapies for psoriasis[J]. Expert Opin Biol Ther, 2019,19(1):45⁃54. doi: 10. 1080/14712598.2019.1555235. |
[5] | Paek SY, Frieder J, Kivelevitch D, et al. IL⁃17 inhibitors for psoriasis[J]. Semin Cutan Med Surg, 2018,37(3):148⁃157. doi: 10.12788/j.sder.2018.051. |
[6] | Cai Y, Shen X, Ding C, et al. Pivotal role of dermal IL⁃17⁃producing γδ T cells in skin inflammation[J]. Immunity, 2011,35(4):596⁃610. doi: 10.1016/j.immuni.2011.08.001. |
[7] | Di Cesare A, Di Meglio P, Nestle FO. The IL⁃23/Th17 axis in the immunopathogenesis of psoriasis[J]. J Invest Dermatol, 2009,129(6):1339⁃1350. doi: 10.1038/jid.2009.59. |
[8] | Lowes MA, Kikuchi T, Fuentes⁃Duculan J, et al. Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells[J]. J Invest Dermatol, 2008,128(5):1207⁃1211. doi: 10. 1038/sj.jid.5701213. |
[9] | Keijsers RR, Joosten I, van Erp PE, et al. Cellular sources of IL⁃17 in psoriasis: a paradigm shift?[J]. Exp Dermatol, 2014,23(11):799⁃803. doi: 10.1111/exd.12487. |
[10] | 王燕芹, 马蕾. Notch信号通路在银屑病发病机制中的研究进展[J]. 中国免疫学杂志, 2018,34(10):1581⁃1584. doi: 10.3969/j.issn.1000⁃484X.2018.10.030. |
[11] | Shibata K, Yamada H, Sato T, et al. Notch⁃Hes1 pathway is required for the development of IL⁃17⁃producing γδ T cells.[J]. Blood, 2011,118(3):586⁃593. doi: 10.1182/blood⁃2011⁃02⁃334995. |
[12] | Chiricozzi A, Romanelli P, Volpe E, et al. Scanning the immunopathogenesis of psoriasis[J]. Int J Mol Sci, 2018,19(1). pii: E179. doi: 10.3390/ijms19010179. |
[13] | Res PC, Piskin G, de Boer OJ, et al. Overrepresentation of IL⁃17A and IL⁃22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis[J/OL]. PLoS One, 2010,5(11):e14108. [2018⁃05⁃18]. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014108. doi: 10.1371/ journal.pone.0014108. |
[14] | Harper EG, Guo C, Rizzo H, et al. Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis[J]. J Invest Dermatol, 2009,129(9):2175⁃2183. doi: 10.1038/jid.2009.65. |
[15] | Gutowska⁃Owsiak D, Schaupp AL, Salimi M, et al. IL⁃17 downregulates filaggrin and affects keratinocyte expression of genes associated with cellular adhesion[J]. Exp Dermatol, 2012,21(2):104⁃110. doi: 10.1111/j.1600⁃0625.2011.01412.x. |
[16] | van der Fits L, Mourits S, Voerman JS, et al. Imiquimod⁃induced psoriasis⁃like skin inflammation in mice is mediated via the IL⁃23/IL⁃17 axis[J]. J Immunol, 2009,182(9):5836⁃5845. doi: 10. 4049/jimmunol.0802999. |
[17] | Amsen D, Helbig C, Backer RA. Notch in T cell differentiation: all things considered[J]. Trends Immunol, 2015,36(12):802⁃814. doi: 10.1016/j.it.2015.10.007. |
[18] | Keerthivasan S, Suleiman R, Lawlor R, et al. Notch signaling regulates mouse and human Th17 differentiation[J]. J Immunol, 2011,187(2):692⁃701. doi: 10.4049/jimmunol.1003658. |
[19] | Jiao Z, Wang W, Hua S, et al. Blockade of Notch signaling ameliorates murine collagen⁃induced arthritis via suppressing Th1 and Th17 cell responses[J]. Am J Pathol, 2014,184(4):1085⁃1093. doi: 10.1016/j.ajpath.2013.12.010. |
[20] | 马蕾, 薛海波, 高梅兰, 等. Notch1信号对银屑病患者外周血Th17细胞分化和功能的影响[J]. 中华皮肤科杂志, 2018,51(3):189⁃193. doi: 10.3760/cma.j.issn.0412⁃4030.2018.03.006 |
[21] | Ma L, Xue H, Qi R, et al. Effect of gamma⁃secretase inhibitor on Th17 cell differentiation and function of mouse psoriasis⁃like skin inflammation[J]. J Transl Med, 2018,16(1):59. doi: 10. 1186/s12967⁃018⁃1442⁃6. |
[22] | Ivanov II, Mckenzie BS, Zhou L, et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL⁃17+ T helper cells[J]. Cell, 2006,126(6):1121⁃1133. doi: 10.1016/j.cell.2006.07.035. |
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