中华皮肤科杂志 ›› 2005, Vol. 38 ›› Issue (2): 80-82.

• 论著 • 上一篇    下一篇

118例志愿者紫外线最小红斑量值测定

王丽英, 陈昆, 常宝珠, 顾恒, 郑家润   

  1. 中国医学科学院、中国协和医科大学皮肤病医院 南京 210042
  • 收稿日期:2004-01-17 出版日期:2005-02-15 发布日期:2005-02-15
  • 通讯作者: 顾恒,E-mail:guhengy@jlonline.com E-mail:guhengy@jlonline.com

Determination of Minimal Erythema Dose of Normal Skin to Ultraviolet Rays

WANG Li-ying, CHEN Kun, CHANG Bao-zhu, GU Heng, ZHENG Jia-run   

  1. Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, China
  • Received:2004-01-17 Online:2005-02-15 Published:2005-02-15

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摘要： 目的 测定118例志愿者长波紫外线(UVA)和中波紫外线(UVB)的最小红斑量(MED)正常值。方法 以SUV1000型日光紫外模拟仪为光源,测定118例健康志愿者和非炎症性皮肤病患者UVA-MED和UVB-MED正常值。结果 UVA-MED均值男性为55J/cm2(18-95J/cm2),女性40J/cm2(15-100J/cm2);UVB-MED均值男性31mJ/cm2(12-95mJ/cm2),女性29mJ/cm2(8-95mJ/cm2)。男性UVA-MED显著高于女性(P<0.05),UVB-MED两性间差异无统计学意义(P>0.05)。皮肤光反应类型为Ⅲ型的受试者UVA-MED和UVB-MED均显著低于Ⅳ型(两种类型皮肤UVA-MED:在男性、女性均P<0.05;UVB-MED:在男性P<0.05,女性P<0.01)。女性的年龄与MED值无关;30-49岁男性UVB-MED低于其他年龄组,UVA-MED与年龄无关。遮光部位测得的UVA-MED和UVB-MED与户外停留时间长短无关。结论 皮肤光反应类型是决定MED的重要因素。

关键词: 最小红斑量, 紫外线

Abstract: Objective To determine the normal range of minimal erythema dose (MED) of normal skin to ultraviolet A (UVA) and B (UVB). Methods The definition of MED is the dose of UVA required to induce a just perceptible erythema on an individual's skin 24 hours after irradiation. One hundred and eighteen subjects including healthy volunteers and patients with noninflammatory skin disorders were enrolled and studied with SUV1000 type UV simulator in March 2002. Results The average MED value for UVA was 55 J/cm2 (range:18-95 J/cm2) in the males, and 40 J/cm2 (range:15-100 J/cm2) in the females. The average MED value for UVB was 31 mJ/cm2 (range:12-95 mJ/cm2) in the males and 29 mJ/cm2 (range:8-95 mJ/cm2) in the females. The MED value for UVA in the males was significantly higher than that in the females (P<0.05). There was no difference of the MED value for UVB between male and female (P>0.05). The MED values for UVA as well as UVB in skin type Ⅲ were significantly lower than those in skin type Ⅳ (UVA-MED:P<0.05 in male, P<0.05 in female; UVB-MED:P<0.05 in male, P<0.01 in female). The correlation between the MED values and age was not found in the female. Compared with other age groups, male aged from 30 to 49 had a much lower MED value for UVB, but not for UVA. Both UVA-MED and UVB-MED of cloth-covered sites were not correlated to the duration of outdoor exposure. Conclusion It is indicated that the MED values of normal skin to UV are mainly dependent on the skin types.

Key words: Minimal erythema dose, Ultraviolet rays