光硬化治疗多形性日光疹的免疫机制及临床应用

doi:10.35541/cjd.20180747

摘要/Abstract

摘要： 【摘要】紫外线光硬化疗法是治疗多形性日光疹（PLE）的一种有效方法，近年来研究显示，窄谱中波紫外线（NB-UVB）可以有效预防PLE复发且有较好的安全性，但其治疗机制尚需进一步阐明，且仍需大样本的临床研究对光硬化治疗的起始剂量、加量原则、治疗频次及维持治疗方案等进行长期追踪和评估，以确定紫外线光硬化疗法在临床中的应用价值。

关键词: 紫外线疗法, 多形性日光疹, 光硬化治疗, 免疫机制, 临床应用

Abstract: 【Abstract】 Ultraviolet light hardening therapy is an effective method for the treatment of polymorphic light eruption （PLE）. Recent studies have shown that narrow-band ultraviolet B （NB-UVB） is effective and safe for the prevention of recurrence of PLE. However, its treatment mechanisms still need further elucidation, and clinical studies with large sample size are needed for long-term tracking and assessment of initial dose of photohardening, dose-addition principle, treatment frequency and maintenance treatment protocols, in order to confirm the clinical application value of ultraviolet light photohardening therapy.

Key words: Ultraviolet therapy, Polymorphic light eruption, Photohardening, Immunological mechanism, Clinical application

龚洋洋徐英萍李慧忠. 光硬化治疗多形性日光疹的免疫机制及临床应用[J]. 中华皮肤科杂志, 2019, 52(11): 856-858.doi:10.35541/cjd.20180747

Gong Yangyang, Xu Yingping, Li Huizhong. Immunological mechanisms and clinical application of photohardening in the treatment of polymorphic light eruption[J]. Chinese Journal of Dermatology, 2019, 52(11): 856-858.doi:10.35541/cjd.20180747

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