特应性皮炎复发控制与组织驻留记忆性T细胞的相关性研究进展

doi:10.35541/cjd.20240192

中华皮肤科杂志 ›› 2025, e20240192.doi: 10.35541/cjd.20240192

特应性皮炎复发控制与组织驻留记忆性T细胞的相关性研究进展

叶慧邓仕琳梁景耀张锡宝

广州医科大学皮肤病研究所广州市皮肤病医院，广州 510095

收稿日期:2024-04-11 修回日期:2024-08-08 发布日期:2025-02-08
通讯作者: 张锡宝 E-mail:zxibao@126.com

Correlations between the control of atopic dermatitis recurrence and tissue-resident memory T cells

Ye Hui, Deng Shilin, Liang Jingyao, Zhang Xibao

Institute of Dermatology, Guangzhou Medical University, Guangzhou Dermatology Hospital, Guangzhou 510095, China

Received:2024-04-11 Revised:2024-08-08 Published:2025-02-08
Contact: Zhang Xibao E-mail:zxibao@126.com

摘要/Abstract

摘要： 【摘要】组织驻留记忆性T细胞在特应性皮炎复发控制中起重要作用，但具体机制尚不明确。深入研究组织驻留记忆性T细胞的生物学功能，有望实现特应性皮炎精准个体化治疗和长期有效控制。本文综述组织驻留记忆性T细胞在皮肤组织中的生物学特性及其在特应性皮炎复发控制中的作用。

关键词: 皮炎, 特应性, T淋巴细胞亚群, 复发, 治疗, 表型, 组织驻留记忆性T细胞

Abstract: 【Abstract】 Tissue-resident memory T cells （TRMs） play a crucial role in controlling atopic dermatitis （AD） relapses, but the exact mechanisms remain unclear. An in-depth study of biological functions of TRMs can potentially lead to precise and individualized treatment and long-term effective control of AD. This review summarizes the biological characteristics of TRMs in skin tissues and their role in controlling the recurrence of AD.

Key words: Dermatitis, atopic, T-lymphocyte subsets, Recurrence, Therapy, Phenotype, Tissue-resident memory T cells

叶慧邓仕琳梁景耀张锡宝. 特应性皮炎复发控制与组织驻留记忆性T细胞的相关性研究进展[J]. 中华皮肤科杂志, 2025,e20240192. doi:10.35541/cjd.20240192

Ye Hui, Deng Shilin, Liang Jingyao, Zhang Xibao. Correlations between the control of atopic dermatitis recurrence and tissue-resident memory T cells[J]. Chinese Journal of Dermatology,2025,e20240192. doi:10.35541/cjd.20240192

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特应性皮炎复发控制与组织驻留记忆性T细胞的相关性研究进展

Correlations between the control of atopic dermatitis recurrence and tissue-resident memory T cells

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