化脓性汗腺炎/反常性痤疮的分型进展

doi:10.35541/cjd.20210252

中华皮肤科杂志 ›› 2023, Vol. 56 ›› Issue (9): 892-895.doi: 10.35541/cjd.20210252

• 综述 • 上一篇

化脓性汗腺炎/反常性痤疮的分型进展

王雯竹1 王宝玺2 何艳艳1 徐浩翔1

¹中国医学科学院北京协和医学院皮肤病医院皮肤科，南京 210042；²中国医学科学院北京协和医学院整形医院皮肤科，北京 100144

收稿日期:2021-03-26 修回日期:2021-10-12 发布日期:2023-09-07
通讯作者: 何艳艳；徐浩翔 E-mail:heyanyan.jsnj@163.com；xbpipi@163.com
作者简介:作者急需开见刊证明且12月见刊，这月定稿 --10.12
基金资助:
国家自然科学基金（82073471、81703148、81673087、81472905）；中国医学科学院医学与健康科技创新工程项目（2016-I2M-1-003）

Clinical phenotypes and genotypes of hidradenitis suppurativa/acne inversa

Wang Wenzhu¹, Wang Baoxi², He Yanyan¹, Xu Haoxiang¹

¹Department of Dermatology, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China; ²Department of Dermatology, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100144, China

Received:2021-03-26 Revised:2021-10-12 Published:2023-09-07
Contact: He Yanyan；Xu Haoxiang E-mail:heyanyan.jsnj@163.com；xbpipi@163.com
Supported by:
National Natural Science Foundation of China （82073471, 81703148, 81673087, 81472905）; CAMS Innovation Fund for Medical Sciences （2016-I2M-1-003）

摘要/Abstract

摘要： 【摘要】化脓性汗腺炎（HS）/反常性痤疮（AI）是一种因毛囊闭锁导致的慢性、复发性、炎症性皮肤病，临床表现差异性大，国内外尚无统一的分型标准，而基于HS/AI临床表现、基因突变及两者相关性的研究丰富了HS/AI的亚型分类。本文综述近年来HS/AI临床表型和基因分型方面的进展及两者之间的联系，以帮助临床医生更好地认识本病，为正确诊断和制定个体化治疗方案提供理论依据。

关键词: 化脓性汗腺炎, 表型, 基因型, 基因型-表型相关性, 反常性痤疮

Abstract: 【Abstract】 Hidradenitis suppurativa（HS）/acne inversa（AI） is a chronic, recurrent and inflammatory skin disease caused by follicular atresia with varying clinical manifestations, and there is no unified classification criteria for it in China and other countries. Based on its clinical characteristics, gene mutations and their correlations, researchers have enriched the subtype classification of HS/AI. This review summarizes recent advances in clinical phenotypes and genotypes of HS/AI as well as their relationships, in order to help clinicians better understand the disease, and provide a theoretical basis for correct diagnosis and individualized treatment strategies.

Key words: Hidradenitis suppurativa, Phenotype, Genotype, Genotype-phenotype correlation, Acne inversa

王雯竹王宝玺何艳艳徐浩翔. 化脓性汗腺炎/反常性痤疮的分型进展[J]. 中华皮肤科杂志, 2023,56(9):892-895. doi:10.35541/cjd.20210252

Wang Wenzhu, Wang Baoxi, He Yanyan, Xu Haoxiang. Clinical phenotypes and genotypes of hidradenitis suppurativa/acne inversa[J]. Chinese Journal of Dermatology, 2023, 56(9): 892-895.doi:10.35541/cjd.20210252

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化脓性汗腺炎/反常性痤疮的分型进展

Clinical phenotypes and genotypes of hidradenitis suppurativa/acne inversa

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